RGD-MODIFIED ALGINATE MICROPARTICLES AS A DRUG RELEASE SYSTEM
- Mota:
- Patentea
- Ikertzailea(k):
- ORIVE ARROYO GORKA ; PEDRAZ MUNOZ JOSE LUIS; HERNANDEZ ROSA MARIA.
- Urtea:
- 2007
- Deskribapena:
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The object of the present invention is to provide particles of a polymeric material containing cells therein, wherein said particles have a strength that is substantially greater than the microcapsules known in the state of the art. Said strength is achieved by means of functionalizing the polymeric material forming the microcapsule with a peptide which can bind to the adhesion proteins of the cell membrane, such that the cells act as cross-linking agents of the matrix resulting in an improvement of the mechanical properties of the matrixes