Perfil académico

Profesora Titular de Universidad

Docencia

“Oinarrizko Biokimika" Medikuntza Gradua (1. maila)

"Biokimika Medikoa" Medikuntza Gradua (1. maila)

"Ikerketa Biomedikorako Sarrera/Introducción a la Investigación Biomédica" Medikuntza Gradua/Grado en Medicina (2. maila/2.o curso)

"Fundamentos de Lipidómica y Liporregulación" Máster en Biología Molecular y Biomedicina

"Bases Moleculares de las Enfermedades Metabólicas" Máster en Investigación Biomédica

"Tecnología Molecular en Biomedicina" Máster en Investigación Biomédica

Publicaciones

Ochoa B, Chico Y, Martínez MJ. Insights Into SND1 Oncogene Promoter Regulation. Front Oncol. 2018. 8:606. doi: 10.3389/fonc.2018.00606. eCollection 2018. https://www.frontiersin.org/articles/10.3389/fonc.2018.00606/full

Navarro-Imaz H, Chico Y, Rueda Y, Fresnedo O. Channeling of newly synthesized fatty acids to cholesterol esterification limits triglyceride synthesis in SND1-overexpressing hepatoma cells. Biochim Biophys Acta Mol Cell Biol Lipids. 2019. 1864(2):137-146. doi: 10.1016/j.bbalip.2018.11.004.

Armengol S, Arretxe E, Enzunza L, Llorente I, Mendibil U, Navarro-Imaz H, Ochoa B, Chico Y, Martínez MJ. REBP-2-driven transcriptional activation of human SND1 oncogene. Oncotarget. 2017. 8(64):108181-108194. doi: 10.18632/oncotarget.22569. eCollection 2017.

Arretxe E, Armengol S, Mula S, Chico Y, Ochoa B, Martínez MJ. Profiling of promoter occupancy by the SND1 transcriptional coactivator identifies downstream glycerolipid metabolic genes upon TNFα stimulation in human hepatoma cells. Nucleic Acids Research 43 (22),10673-10688, 2015.http://www.ncbi.nlm.nih.gov/pubmed/26323317

Sandra Armengol, Enara Arretxe, Leire Enzunza, Sarai Mula, Begoña Ochoa, Yolanda Chico, María José Martínez. The promoter of cell growth- and RNA protection-associated SND1 gene is activated by endoplasmic reticulum stress in human hepatoma cells. BMC Biochemistry 15, 25, 2014. DOI: 10.1186/s12858-014-0025-2014. http://www.ncbi.nlm.nih.gov/pubmed/25494629

Sandra Armengol, Enara Arretxe, Lorena Rodríguez, Begoña Ochoa, Yolanda Chico, María José Martínez. NF-kB, Sp1 and NF-Y as transcriptional regulators of human SND1 gene. Biochemie 95, 735-742, 2013. http://www.ncbi.nlm.nih.gov/pubmed/23160072

Patricia Aspichueta, Nerea Bartolomé, Xavier Buqué, María José Martínez, Begoña Ochoa and Yolanda Chico. Disrupted VLDL features and lipoprotein metabolism in sepsis. Libro: Dyslipidemia- From prevention to treatment. Capítulo: 10, 199-214, 2012. Editor Roya Kelishadi, ISBN 978-953-307-904-2, InTech (on line) DOI: 10.5772/29421 http://www.intechopen.com/books/dyslipidemia-from-prevention-to-treatment/disrupted-vldl-features-and-lipoprotein-metabolism-in-sepsis

Nerea Bartolomé, Patricia Aspichueta, María José Martínez, Mercedes Vázquez-Chantada, María Luz Martínez-Chantar, Yolanda Chico and Begoña Ochoa, Biphasic adaptative responses in VLDL metabolism and lipoprotein homeostasis during Gram-negative endotoxemia. Innate Immunity 18, 89-99, 2012

Sánchez-Garrido MA, Chico Y, González R, Ranchal I, González-Rubio S, Hidalgo AB, Díaz-López C, Costán G, Padillo FJ, De la Mata M, Ochoa B, Muntané J. Interleukin-6 is associated with liver lipid homeostasis but not with cell death in experimental hepatic steatosis. Innate Immun. 2009. 15(6):337-49. doi: 10.1177/1753425909104900.

N. Bartolomé, B. Arteta, M.J. Martínez, B. Ochoa, Y. Chico. Kuppfer cell products and interleukin 1 directly promote VLDL secretion and apoB mRNA upregulation in rodent hepatocytes. Innate Immunity 14 (4), 255-266, 2008.