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Noureddin M, Truong E, Mayo R, Martínez-Arranz I, Mincholé I, Banales JM, Arrese M, Cusi K, Arias-Loste MT, Bruha R, Romero-Gómez M, Iruzubieta P, Aller R, Ampuero J, Calleja JL, Ibañez-Samaniego L, Aspichueta P, Martín-Duce A, Kushner T, Ortiz P, Harrison SA, Anstee QM, Crespo J, Mato JM, Sanyal AJ.
Serum identification of at-risk MASH: The metabolomics-advanced steatohepatitis fibrosis score (MASEF)
Hepatology.,
2024
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Manka P, Coombes JD, Sydor S, Swiderska-Syn MK, Best J, Gauthier K, van Grunsven LA, Oo YH, Wang C, Diehl AM, Hönes GS, Moeller LC, Figge A, Boosman RJ, Faber KN, Tannapfel A, Goetze O, Aspichueta P, Lange CM, Canbay A, Syn WK.
Thyroid hormone receptor alpha modulates fibrogenesis in hepatic stellate cells
Liver Int.,
2024
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Capelo-Diz A, Lachiondo-Ortega S, Fernández-Ramos D, Cañas-Martín J, Goikoetxea-Usandizaga N, Serrano-Maciá M, González-Rellan MJ, Mosca L, Blazquez-Vicens J, Tinahones-Ruano A, Fondevila MF, Buyan M, Delgado TC, Gutierrez de Juan V, Ayuso-García P, Sánchez-Rueda A, Velasco-Avilés S, Fernández-Susavila H, Riobello-Suárez C, Dziechciarz B, Montiel-Duarte C, Lopitz-Otsoa F, Bizkarguenaga M, Bilbao-García J, Bernardo-Seisdedos G, Senra A, Soriano-Navarro M, Millet O, Díaz-Lagares Á, Crujeiras AB, Bao-Caamano A, Cabrera D, van Liempd S, Tamayo-Carro M, Borzacchiello L, Gomez-Santos B, Buqué X, Sáenz de Urturi D, González-Romero F, Simon J, Rodríguez-Agudo R, Ruiz A, Matute C, Beiroa D, Falcon-Perez JM, Aspichueta P, Rodríguez-Cuesta J, Porcelli M, Pajares MA, Ameneiro C, Fidalgo M, Aransay AM, Lama-Díaz T, Blanco MG, López M, Villa-Bellosta R, Müller TD, Nogueiras R, Woodhoo A, Martínez-Chantar ML, Varela-Rey M.
Hepatic levels of S-adenosylmethionine regulate the adaptive response to fasting
Cell Metab.,
2023
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Aspichueta P, Zeisel MB.
miR-21p-5p coordinates biological pathways to promote MASLD progression
Liver Int.,
2023
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Marsal-Beltran A, Rodríguez-Castellano A, Astiarraga B, Calvo E, Rada P, Madeira A, Rodríguez-Peña MM, Llauradó G, Núñez-Roa C, Gómez-Santos B, Maymó-Masip E, Bosch R, Frutos MD, Moreno-Navarrete JM, Ramos-Molina B, Aspichueta P, Joven J, Fernández-Real JM, Quer JC, Valverde ÁM, Pardo A, Vendrell J, Ceperuelo-Mallafré V, Fernández-Veledo S.
Protective effects of the succinate/SUCNR1 axis on damaged hepatocytes in NAFLD
Metabolism.,
2023
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Aurrekoetxea I, Gomez-Santos B, Apodaka-Biguri M, Ruiz de Gauna M, Gonzalez-Romero F, Buqué X, Aspichueta P.
In Vivo Tissue Lipid Uptake in Antisense Oligonucleotide (ASO)-Treated Mice
Methods Mol Biol.,
2023
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Gomez-Santos B, Saenz de Urturi D, Buqué X, Aurrekoetxea I, Nieva A, Fernández-Puertas I, Aspichueta P.
In Vivo Hepatic Triglyceride Secretion Rate in Antisense Oligonucleotide (ASO)-Treated Mice
Methods Mol Biol.,
2023
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Saliba-Gustafsson P, Justesen JM, Ranta A, Sharma D, Bielczyk-Maczynska E, Li J, Najmi LA, Apodaka M, Aspichueta P, Björck HM, Eriksson P, Franco-Cereceda A, Gloudemans M, Mujica E, den Hoed M, Assimes TL, Quertermous T, Carcamo-Orive I, Park CY, Knowles JW.
A functional genomic framework to elucidate novel causal non-alcoholic fatty liver disease genes
medRxiv,
2023
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Huergo-Baños C, Velasco V, Garate J, Fernández R, Martín-Allende J, Zabalza I, Artola JL, Martí RM, Asumendi A, Astigarraga E, Barreda-Gómez G, Fresnedo O, Ochoa B, Boyano MD, Fernández JA.
Lipid fingerprint-based histology accurately classifies nevus, primary melanoma, and metastatic melanoma samples.
Int J Cancer,
2023
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Emmanuel Berlin, Veronica Lizano-Fallas, Ana Carrasco Del Amor, Olatz Fresnedo, Susana Cristobal
Nonionic Surfactants can Modify the Thermal Stability of Globular and Membrane Proteins Interfering with the Thermal Proteome Profiling Principles to Identify Protein Targets
Anal Chem,
2023
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Lucía Martín-Saiz, Beatriz Abad-García, Jon D Solano-Iturri, Lorena Mosteiro, Javier Martín-Allende, Yuri Rueda, Amparo Pérez-Fernández, Miguel Unda, Pedro Coterón-Ochoa, Aintzane Goya, Alberto Saiz, Jennifer Martínez, Begoña Ochoa, Olatz Fresnedo, Gorka Larrinaga, José A Fernández
Using the Synergy between HPLC-MS and MALDI-MS Imaging to Explore the Lipidomics of Clear Cell Renal Cell Carcinoma
Anal Chem,
2023
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Begoña Lavin, Thomas R Eykyn, Alkystis Phinikaridou, Aline Xavier, Shravan Kumar, Xabier Buqué, Patricia Aspichueta, Carlos Sing-Long, Marco Arrese, René M Botnar, Marcelo E Andia
Characterization of hepatic fatty acids using Magnetic Resonance Spectroscopy for the assessment of treatment response to Metformin in an eNOS-/- mouse model of metabolic NAFLD-NASH
NMR Biomed,
2023
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Ruben Nogueiras, Patricia Aspichueta
Expanding the roles of the renin-angiotensin system: Drug-induced liver injury
J Hepatol,
2023
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Fresnedo O, Abad-Garcia B, Rueda Y
Tri-Reagent Homogenate Is a Suitable Starting Material for UHPLC-MS Lipidomic Analysis
Separations,
2022;
9,
268 - 275
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Marta Martín-Fernández, Víctor Arroyo, Carmen Carnicero, Rebeca Sigüenza, Reyes Busta, Natalia Mora, Beatriz Antolín, Eduardo Tamayo, Patricia Aspichueta, Irene Carnicero-Frutos, Hugo Gonzalo-Benito, Rocío Aller
Role of Oxidative Stress and Lipid Peroxidation in the Pathophysiology of NAFLD
Antioxidants (Basel),
2022
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Mohaddase Hamidi, Ainhoa Eriz, Jone Mitxelena, Larraitz Fernandez-Ares, Igor Aurrekoetxea, Patricia Aspichueta, Ainhoa Iglesias-Ara, Ana M Zubiaga
Targeting E2F Sensitizes Prostate Cancer Cells to Drug-Induced Replication Stress by Promoting Unscheduled CDK1 Activity
Cancers (Basel),
2022
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Ibone Labiano, Aloña Agirre-Lizaso, Paula Olaizola, Anne Echebarria, Maider Huici-Izagirre, Irene Olaizola, Aitor Esparza-Baquer, Omar Sharif, Elizabeth Hijona, Piotr Milkiewicz, Malgorzata Milkiewicz, Francisco González-Romero, Patricia Aspichueta, Maria J Monte, Jose J G Marin, Mihael Vucur, Tom Luedde, Marco Marzioni, Derek A Mann, Luis Bujanda, Pedro M Rodrigues, Jesus M Banales, Maria J Perugorria
TREM-2 plays a protective role in cholestasis by acting as a negative regulator of inflammation
J Hepatol,
2022
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Paula Olaizola, Pedro M Rodrigues, Francisco J Caballero-Camino, Laura Izquierdo-Sanchez, Patricia Aspichueta, Luis Bujanda, Nicholas F Larusso, Joost P H Drenth, Maria J Perugorria, Jesus M Banales
Genetics, pathobiology and therapeutic opportunities of polycystic liver disease
Nat Rev Gastroenterol Hepatol,
2022
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Paula Olaizola, Pui Yuen Lee-Law, Maite G Fernandez-Barrena, Laura Alvarez, Massimiliano Cadamuro, Mikel Azkargorta, Colm J O'Rourke, Francisco J Caballero-Camino, Irene Olaizola, Rocio I R Macias, Jose J G Marin, Marina Serrano-Maciá, Maria L Martinez-Chantar, Matias A Avila, Patricia Aspichueta, Diego F Calvisi, Matthias Evert, Luca Fabris, Rui E Castro, Felix Elortza, Jesper B Andersen, Luis Bujanda, Pedro M Rodrigues, Maria J Perugorria, Jesus M Banales
Targeting NAE1-mediated protein hyper-NEDDylation halts cholangiocarcinogenesis and impacts on tumor-stroma crosstalk in experimental models
J Hepatol,
2022
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Diego Sáenz de Urturi, Xabier Buqué, Begoña Porteiro, Cintia Folgueira, Alfonso Mora, Teresa C. Delgado, Endika Prieto-Fernández, Paula Olaizola, Beatriz Gómez-Santos, Maider Apodaka-Biguri, Francisco González-Romero, Ane Nieva-Zuluaga, Mikel Ruiz de Gauna, Naroa Goikoetxea-Usandizaga, Juan Luis García-Rodríguez, Virginia Gutierrez de Juan, Igor Aurrekoetxea, Valle Montalvo-Romeral, Eva M. Novoa, Idoia Martín-Guerrero, Marta Varela-Rey, Sanjay Bhanot, Richard Lee, Jesus M. Banales, Wing-Kin Syn, Guadalupe Sabio, María L. Martínez-Chantar, Rubén Nogueiras, Patricia Aspichueta
Methionine adenosyltransferase 1a antisense oligonucleotides activate the liver-brown adipose tissue axis preventing obesity and associated hepatosteatosis
NATURE COMMUNICATIONS,
2022
