FULLAONDO_ASIER

Asier Fullaondo

Introduction

Phone: 94 601 5696
Emailasier.fullaondo@ehu.es
Office Location: School of Science and Technology,Room: F1.P0.4
Research Group: MOLECULAR BIOLOGY OF CANCER
Personal Web Pages:

Teaching profile

I began my University teaching in 1995. During this time, I have participated in teaching the subjects of Genetics (compulsory) and Cytogenetics and Human Genetics (optional) in the Degree of Medicine, at the School of Medicine and Dentistry.Currently, I am a lecturer at the School of Science and Technology and teach the subjects ofGenetics in the Degree of Biology, and Genomics in the Degrees of Biochemistry and Molecular Biology and Biotechnology.

Regarding post-graduate teaching, I am one of the lecturers in the courses Fundamentals of Genomics, Proteomics and Bioinformatics and Proteomikaren Oinarriak. These courses are part of the Master in Molecular Biology and Biomedicine.

In addition, I supervise graduate student projects in the Degree of Biology and the Degree of Biochemistry. I also supervise master student projects within the Master in Molecular Biology and Biomedicine.

Research profile

I received my Ph.D. in 1999 with a study on "Genetic characterization of the potato cyst nematode".
I did my postdoctoral stay at the Netherlands Proteomic Center, where I specialized in proteomic analysis applied to cell proliferation and differentiation processes. My research is linked to the research line directed by Dr. Ana Zubiaga, mainly focused on the genetic regulation of cell cycle and tumor development. Besides, I have participated in other research lines related to the analysis of genotoxicity.

Selected publications (last 5 years)

1: Prieto G, Rodríguez JA, Fullaondo A. Enhancing prediction of short linear
protein motifs with Wregex 3.0. Comput Struct Biotechnol J. 2024 Jul
17;23:2978-2984. doi: 10.1016/j.csbj.2024.07.013. PMID: 39135888; PMCID:
PMC11318550.

2: González A, Fullaondo A, Rodríguez J, Tirnauca C, Odriozola I, Odriozola A.
Conjugated linoleic acid metabolite impact in colorectal cancer: a potential
microbiome-based precision nutrition approach. Nutr Rev. 2024 May 10:nuae046.
doi: 10.1093/nutrit/nuae046. Epub ahead of print. PMID: 38728013.

3: Anitua E, Troya M, Zalduendo M, Tierno R, Alkhraisat MH, Osinalde N,
Fullaondo A, Zubiaga AM. Improving the mechanical and biological functions of
cell sheet constructs: The interplay of human-derived periodontal ligament stem
cells, endothelial cells and plasma rich in growth factors. Biomed Pharmacother.
2024 May;174:116599. doi: 10.1016/j.biopha.2024.116599. Epub 2024 Apr 18. PMID:
38640711.

4: Peña-Cearra A, Castelo J, Lavín JL, Gonzalez-Lopez M, Pascual-Itoiz MA,
Fuertes M, Gutiérrez de Juan V, Bárcena L, Martín-Ruiz I, Pellón A, Seoane I,
Barriales D, Palacios A, Fullaondo A, Rodríguez-Lago I, Martinez-Chantar ML,
Aransay AM, Rodriguez H, Anguita J, Abecia L. Mitochondrial dysfunction-
associated microbiota establishes a transmissible refractory response to anti-
TNF therapy during ulcerative colitis. Gut Microbes. 2023 Dec;15(2):2266626.
doi: 10.1080/19490976.2023.2266626. Epub 2023 Oct 16. PMID: 37842919; PMCID:
PMC10586225.

5: Peña-Cearra A, Song D, Castelo J, Palacios A, Lavín JL, Azkargorta M, Elortza
F, Fuertes M, Pascual-Itoiz MA, Barriales D, Martín-Ruiz I, Fullaondo A, Aransay
AM, Rodríguez H, Palm NW, Anguita J, Abecia L. Mitochondrial dysfunction
promotes microbial composition that negatively impacts on ulcerative colitis
development and progression. NPJ Biofilms Microbiomes. 2023 Oct 7;9(1):74. doi:
10.1038/s41522-023-00443-y. PMID: 37805634; PMCID: PMC10560208.

6: Peña-Cearra A, Pascual-Itoiz MA, Lavín JL, Fuertes M, Martín-Ruiz I, Castelo
J, Palacios A, Barriales D, Fullaondo A, Aransay AM, Rodríguez H, Anguita J,
Abecia L. Mitochondrial complex I dysfunction alters the balance of soluble and
membrane-bound TNF during chronic experimental colitis. Sci Rep. 2022 Jun
15;12(1):9977. doi: 10.1038/s41598-022-13480-y. PMID: 35705557; PMCID:
PMC9200762.

7: Pascual-Itoiz MA, Peña-Cearra A, Martín-Ruiz I, Lavín JL, Simó C, Rodríguez
H, Atondo E, Flores JM, Carreras-González A, Tomás-Cortázar J, Barriales D,
Palacios A, García-Cañas V, Pellón A, Fullaondo A, Aransay AM, Prados-Rosales R,
Martín R, Anguita J, Abecia L. The mitochondrial negative regulator MCJ
modulates the interplay between microbiota and the host during ulcerative
colitis. Sci Rep. 2020 Jan 17;10(1):572. doi: 10.1038/s41598-019-57348-0. PMID:
31953445; PMCID: PMC6969106.

8: Mitxelena J, Apraiz A, Vallejo-Rodríguez J, García-Santisteban I, Fullaondo
A, Alvarez-Fernández M, Malumbres M, Zubiaga AM. An E2F7-dependent
transcriptional program modulates DNA damage repair and genomic stability.
Nucleic Acids Res. 2019 Aug 22;47(14):7716-7717. doi: 10.1093/nar/gkz587.
Erratum for: Nucleic Acids Res. 2018 May 18;46(9):4546-4559. doi:
10.1093/nar/gky218. PMID: 31269207; PMCID: PMC6698732.

9: Peñalver-González B, Vallejo-Rodríguez J, Mentxaka G, Fullaondo A, Iglesias-
Ara A, Field SJ, Zubiaga AM. Golgi Oncoprotein <i>GOLPH3</i> Gene Expression Is
Regulated by Functional E2F and CREB/ATF Promoter Elements. Genes (Basel). 2019
Mar 25;10(3):247. doi: 10.3390/genes10030247. PMID: 30934642; PMCID: PMC6471639.

10: González A, Fullaondo A, Odriozola A. Impact of evolution on lifestyle in
microbiome. Adv Genet. 2024;111:149-198. doi: 10.1016/bs.adgen.2024.02.003. Epub
2024 Mar 15. PMID: 38908899.

11: González A, Fullaondo A, Odriozola A. Techniques, procedures, and
applications in microbiome analysis. Adv Genet. 2024;111:81-115. doi:
10.1016/bs.adgen.2024.01.003. Epub 2024 Feb 5. PMID: 38908906.

12: González A, Fullaondo A, Odriozola A. Microbiota-associated mechanisms in
colorectal cancer. Adv Genet. 2024;112:123-205. doi:
10.1016/bs.adgen.2024.05.002. Epub 2024 Jul 25. PMID: 39396836.

13: González A, Odriozola I, Fullaondo A, Odriozola A. Microbiota and
detrimental protein derived metabolites in colorectal cancer. Adv Genet.
2024;112:255-308. doi: 10.1016/bs.adgen.2024.06.001. Epub 2024 Jul 8. PMID:
39396838.

14: González A, Fullaondo A, Odriozola I, Odriozola A. Microbiota and other
detrimental metabolites in colorectal cancer. Adv Genet. 2024;112:309-365. doi:
10.1016/bs.adgen.2024.08.006. Epub 2024 Sep 26. PMID: 39396839.

15: González A, Fullaondo A, Odriozola A. Host genetics and microbiota data
analysis in colorectal cancer research. Adv Genet. 2024;112:31-81. doi:
10.1016/bs.adgen.2024.08.007. Epub 2024 Sep 27. PMID: 39396840.

16: González A, Fullaondo A, Odriozola I, Odriozola A. Microbiota and beneficial
metabolites in colorectal cancer. Adv Genet. 2024;112:367-409. doi:
10.1016/bs.adgen.2024.08.002. Epub 2024 Sep 26. PMID: 39396841.

17: González A, Badiola I, Fullaondo A, Rodríguez J, Odriozola A. Personalised
medicine based on host genetics and microbiota applied to colorectal cancer. Adv
Genet. 2024;112:411-485. doi: 10.1016/bs.adgen.2024.08.004. Epub 2024 Sep 27.
PMID: 39396842.

18: González A, Fullaondo A, Odriozola A. Host genetics-associated mechanisms in
colorectal cancer. Adv Genet. 2024;112:83-122. doi:
10.1016/bs.adgen.2024.08.003. Epub 2024 Sep 27. PMID: 39396843.