Biochemistry is one of the basic subjects of the first course of the Dentistry Degree. The subject serves as support for other subjects such as Biology or Physiology. To take the subject it is highly recommended to master the basic principles of organic chemistry.

In the professional field, this subject serves as a basis for knowledge of oral disease.

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1 Know the main biomolecules and their function in the human organism

2 Know the main metabolic pathways

3 Know the basic mechanisms of molecular biology (gene expression, transmission and regulation)

4 Distinguish the basic biochemistry of the tooth and periodontal tissues in normal and pathological states

5 Getting around in the Biochemistry laboratory

6 Develop teamwork

MASTER CLASSES



1 Thematic Block: Introduction to Biochemistry

Topic 1: Water and Solutions

Topic 2: pH and Buffers

2 Thematic Block: Enzymatic Catalysis

Topic 3: Enzymes

Topic 4: Enzyme Regulation

Topic 5: Vitamins

3 Thematic Block: Metabolism

Topic 6: Introduction to Metabolism

Topic 7: Beginning and End of Metabolism

Topic 8: Carbohydrate Catabolism

Topic 9: Lipid Catabolism

Topic 10: Protein Catabolism

Topic 11: Carbohydrate Anabolism

Topic 12: Lipid Anabolism

4 Thematic Block: Transmission of Genetic Information

Topic 13: DNA synthesis

Topic 14: RNA synthesis

Topic 15: Protein Synthesis

Topic 16: Regulation of Gene Expression

5 Thematic Block: Biochemistry of the Oral-Dental Environment

Topic 17: Chemical composition of teeth

Topic 18: Biochemical aspects of dental pathologies

Topic 19: Biochemistry of fluorinated compounds





CLASSROOM PRACTICES



1 Classroom Practice: Concentration Measures

2 Classroom Practice: Tonicity and pH Measurement

3 Classroom Practice: Enzyme Kinetics

4 Classroom Practice: Bioenergetics





SEMINARS (directed works)

1 Seminar: Carbohydrates

2 Seminar: Lipids

3 Seminar: Proteins

4 Seminar: Nucleid Acids





LABORATORY PRACTICES

1 Laboratory Practice: Introduction to the Laboratory

2 Laboratory Practice: Homogenization and Centrifugation

3 Laboratory Practice: Preparation of Solutions

4 Laboratory Practice: Colorimetry

5 Laboratory Practice: Lipid Extraction

6 Laboratory Practice: Lipid Analysis (TLC)

7 Laboratory Practice: Enzyme Kinetics I

8 Laboratory Practice: Enzyme Kinetics II

9 Laboratory Practice: Determination of Salivary Amylase Activity

10 Laboratory Practice: Serum Protein Electrophoresis

11 Laboratory Practice: Gel filtration (molecular sieving)

Various methodologies are used: group work on various structural topics in biochemistry, master classes and practical laboratory classes, all to acquire basic knowledge of biochemistry.

• Continuous Assessment System
• Final Assessment System
• Tools and qualification percentages:
  • Written test to be taken (%): 80
  • Realization of Practical Work (exercises, cases or problems) (%): 5
  • Team projects (problem solving, project design)) (%): 5
  • Exhibition of works, readings ... (%): 10

The written exam consists of test questions, short answer questions and exercises. It is valued with 8 points. The practices, work carried out and their presentation are valued with 2 points.



In accordance with the new Regulations for Student Evaluation of Undergraduate Degrees (BOPV nº50, March 13, 2017):

-1. Students may waive the continuous (or mixed) evaluation system and opt for the final evaluation, regardless of whether or not they have participated in the aforementioned continuous evaluation (Article 8.3).

-2. The procedure and deadlines that students must follow to carry out the resignation will be at least 9 weeks for semester subjects, counting from the beginning of the semester, in accordance with the center's academic calendar. Thus, interested students must submit in writing to the responsible teaching staff their resignation from the continuous (or mixed) evaluation in accordance with the established procedure and deadlines (Article 8.3).



In the final evaluation, the master teaching will be evaluated in a final test that will consist of multiple choice questions, short questions and a topic to be developed. The grade for this type of teaching will contribute 60-80% to the final grade.

Laboratory practices will be evaluated through exercises, evaluated in each practice, and will constitute 20-40% of the final grade.



Likewise, in accordance with the new Regulatory Regulations for the Evaluation of Students of Degree Degrees (BOPV nº50, March 13, 2017), it is established to adopt for the waiver of the call for evaluation of the 4th course of the Degree in Biochemistry and Biology Molecular the following criteria:

-1. Students may waive the evaluation call, which implies that it will not be counted and will be recorded as Not Presented (Article 12.1).

-2. In the case of continuous evaluation, students may withdraw from the call within a period that, at least, will be up to one month before the end date of the teaching period for the corresponding subject. This resignation must be submitted in writing to the teaching staff responsible for the subject (Article 12.2).

-3. When it comes to final evaluation, failure to take the test set on the official exam date will mean automatic resignation from the corresponding call (Article 12.3).



During the development of the evaluation tests, unless the teaching team authorizes the specific use of certain devices or teaching material, the use of books, notes or notes, as well as telephone, electronic, computer, or other devices or devices will be prohibited. another type, by the students. In any case of dishonest or fraudulent practice, the provisions of the protocol on academic ethics and prevention of dishonest or fraudulent practices in evaluation tests and academic work at the UPV/EHU will be applied.



If the evaluation tests cannot be carried out in person, they will be adapted to a non-face-to-face evaluation.

The written exam consists of test questions, short answer questions and exercises. It is valued with 8 points. The practices, work carried out and their presentation are valued with 2 points.



In accordance with the new Regulations for Student Evaluation of Undergraduate Degrees (BOPV nº50, March 13, 2017):

-1. Students may waive the continuous (or mixed) evaluation system and opt for the final evaluation, regardless of whether or not they have participated in the aforementioned continuous evaluation (Article 8.3).

-2. The procedure and deadlines that students must follow to carry out the resignation will be at least 9 weeks for semester subjects, counting from the beginning of the semester, in accordance with the center's academic calendar. Thus, interested students must submit in writing to the responsible teaching staff their resignation from the continuous (or mixed) evaluation in accordance with the established procedure and deadlines (Article 8.3).



In the final evaluation, the master teaching will be evaluated in a final test that will consist of multiple choice questions, short questions and a topic to be developed. The grade for this type of teaching will contribute 60-80% to the final grade.

Laboratory practices will be evaluated through exercises, evaluated in each practice, and will constitute 20-40% of the final grade.



Likewise, in accordance with the new Regulatory Regulations for the Evaluation of Students of Degree Degrees (BOPV nº50, March 13, 2017), it is established to adopt for the waiver of the call for evaluation of the 4th course of the Degree in Biochemistry and Biology Molecular the following criteria:

-1. Students may waive the evaluation call, which implies that it will not be counted and will be recorded as Not Presented (Article 12.1).

-2. In the case of continuous evaluation, students may withdraw from the call within a period that, at least, will be up to one month before the end date of the teaching period for the corresponding subject. This resignation must be submitted in writing to the teaching staff responsible for the subject (Article 12.2).

-3. When it comes to final evaluation, failure to take the test set on the official exam date will mean automatic resignation from the corresponding call (Article 12.3).



During the development of the evaluation tests, unless the teaching team authorizes the specific use of certain devices or teaching material, the use of books, notes or notes, as well as telephone, electronic, computer, or other devices or devices will be prohibited. another type, by the students. In any case of dishonest or fraudulent practice, the provisions of the protocol on academic ethics and prevention of dishonest or fraudulent practices in evaluation tests and academic work at the UPV/EHU will be applied.



If the evaluation tests cannot be carried out in person, they will be adapted to a non-face-to-face evaluation.

Lab coat for practical laboratory classes.
Facial mask.
Laptop or tablet to take the exam and on line questionnaires.

Basic bibliography

- Macarulla JM, Goñi FM. ¿Biomoléculas¿. Ed Reverté (3ª ed) 1993



- Macarulla JM, Goñi FM. ¿Bioquímica Humana¿. Ed Reverté (2ª ed) 1994



- Lozano JA, Galindo JD, García-Borrón JC, Martínez-Liarte JH, Peñafiel R, Solano F. Bioquímica y biología molecular para ciencias de la salud. Ed McGraw-Hill Interamaricana (3ª ed) 2005



- Devlin TM. ¿Bioquímica. Libro de texto con aplicaciones clínicas¿ Ed Reverté (4ª edición) 2004.



- Murray R, Granner DK, Rodwell VW. ¿HARPER. Bioquímica Ilustrada¿. Ed El Manual Moderno (17ª Ed) 2007



- Nelson DL & Cox MM. ¿LEHNINGER Principles of Biochemistry¿ (5th edition), 2008. En Castellano: ¿LEHNINGER PRINCIPIOS DE BIOQUÍMICA¿ Ediciones Omega (4ª Edición), 2005.



- Voet D, Voet JG & Pratt CW . ¿Fundamentos de Bioquímica¿. Ed Panamericana (2ª edición) 2006.



- STRYER L, Berg JM & Tymoczko JL. ¿Bioquímica¿. Ed. Reverté (6ª Edicion), 2007.



- Wilson, K., Walker, J. ¿Principles and techniques of practical Biochemistry¿., Cambridge Univ. Press (5th ed) 2000.



- Atance, J.R., ¿Bioquímica bucodental¿ Ed. Síntesis, 1996



- Ferguson ¿Oral Bioscience¿, Ed. Churchill Livingstone, 2006



- Williams RAD, Elliott JC.¿Bioquímica dental básica y aplicada¿. Ed El Manual Moderno (2ª ed) 1990

In-depth bibliography

- Murray R, Granner DK, Rodwell VW. HARPER. Bioquímica Ilustrada. Ed El Manual Moderno (17ª Ed) 2007

- Devlin TM. Bioquímica. Libro de texto con aplicaciones clínicas Ed Reverté (4ª edición) 2004.

- Voet D, Voet JG & Pratt CW . Fundamentos de Bioquímica. Ed Panamericana (2ª edición) 2006.

- STRYER L, Berg JM & Tymoczko JL. Bioquímica. Ed. Reverté (6ª Edicion), 2007.

- Atance, J.R., Bioquímica bucodental Ed. Síntesis, 1996

- Ferguson Oral Bioscience, Ed. Churchill Livingstone, 2006

Journals

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Web addresses

http://www.ehu.es/biomoleculas/
(Curso orientado a estudiantes de Bioquímica y Biología Molecular realizado por Juan Manuel González Mañas, Profesor Titular del Departamento de Bioquímica y Biología Molecular de la Universidad del País Vasco)

http://www.galeon.com/filoesp/ciencia/quimica/bioquimica.htm
(Guía a los recursos de Bioquímica en español disponibles en Internet)

http://www.um.es/molecula/indice.htm

http://www2.uah.es/biomodel/

http://tsbioquimica.blogspot.com/search/label/bioquimica


Odontología:
http://www.uv.es/salgado/odonto/.files/
(Página web de la Universidad de Valencia con documentos electrónicos sobre bioquímica dental. Indice del Temario)

http://www.dentistry.leeds.ac.uk/biochem/thcme/home.html