University of the Basque Country University of the Basque Country

Breadcrumb

Info_Biomedicina_Genomica-Secuenciacion_aplicaciones

GENERAL GENOMICS SERVICE SEQUENCING AND GENOTYPING UNIT

Applications

The study of the genome has become transformed into a molecular tool of great potential in research into different areas of knowledge in Biological, Environmental, Food, Biomedical and Biotechnological Science.
Applications for DNA analysis cover many fields, among which we wish to draw attention to the following:

Human Health and Pharmacogenetics

  • Studies involving tying and association aimed at identifying genomic variants that entail a risk of contracting diseases or resulting in adverse responses to drugs.
  • Molecular oncology: detection of mutations in oncogenes and tumour suppressor genes.
  • Characterization, diagnosis and prognosis of human diseases.
  • Individualized prescribing of therapuetic treatment

Legal medicine

  • Identification of individuals.
  • Paternity testing.

Veterinary medicine and food

  • Paternity and genetic identification tests in diverse animal species aimed at controlling affiliations and verification of pedigrees.
  • Traceability of animals and their by-products.
  • Identification of genes: referring to characters of financial and productive importance, such as sensitivity or resistance to diseases (QTLs, candidate genes).
  • Detection of pathogens.
  • Genetic authentification of foods.

Molecular Biology

  • Phylogenetic studies and studies involving the evolution of organisms.
  • Cloning, construction of plasmids, etc.
  • Design of hybridization probes.
  • Detection of mutations.
  • Studies into genetic regulation of the cellular cycle and other biological mechanisms.
  • Epigenetics.

Environmental

  • Identification of animal and plant species.
  • Phylogenetic studies and evolution of organisms.
  • Conservation of animal genetic resources: phylogenetic resources and analysis of the diversity of local populations of animals via the application of DNA polymorphisms (sheep, horses, cattle, Apis mellifera, Lepus europeus, Cervus elaphus, etc.).
  • Agriculture: identification of genetically-modified organisms, studies into resistance to herbicides and/or pesticides, etc.
  • Microbiology: identification of bacterial species.
  • Analysis of microorganisms in water samples.
  • Virology.