Development of non-viral vectors for gene therapy: application in the treatment of ocular disease (X-linked juvenile retinoschisis), metabolic diseases (Fabry disease) and, infectious diseases (hepatitis C).
Development of micro- and nanoparticulate systems as drug delivery systems. Biopharmaceutical and pharmacokinetic evaluation.
Pharmacokinetic analysis of new drugs: drug levels quantification in biological samples, population pharmacokinetics.
Pharmacokinetic/pharmacodynamic analysis in antibiotherapy: application to surgical prophylaxis, critically ill patients, renal replacement continuous techniques, …
Pharmacotherapeutic and pharmacoeconomic evaluation of medicines. Pharmaceutical care in polymedicated patients.
Regulation of biotechnological medicines. Biosimilar medicines.
Schematic figure of the transport mechanisms used by different lipid nanoparticles (Beloqui et al., J Control Rel, 2013)
