Neuropsychopharmacology Research Group

• Almodóvar-Payá C, Guardiola-Ripoll M, Giralt-López M, Oscoz-Irurozqui M, Canales-Rodríguez EJ, Madre M, Soler-Vidal J, Ramiro N, Callado LF, Arias B, Gallego C, Pomarol-Clotet E, Fatjó-Vilas M.  NRN1 epistasis with BDNF and CACNA1C: mediation effects on symptom severity through neuroanatomical changes in schizophrenia Brain Structure and Function,  2024;  229(5),  1299 - 1315
• Bulduk BK, Tortajada J, Valiente-Pallejà A, Callado LF, Torrell H, Vilella E, Meana JJ, Muntané G, Martorell L.  High number of mitochondrial DNA alterationsin postmortem brain tissue of patients with schizophrenia compared to healthycontrols Psychiatry Research,  2024;  337:115928
• Costas-Insua C, Hermoso-López A, Moreno E, Montero-Fernández C, Álvaro- Blázquez A, Maroto IB, Sánchez-Ruiz A, Diez-Alarcia R, Blázquez C, Morales P, Canela EI, Casadó V, Urigüen L, Perea G, Bellocchio L, Rodríguez-Crespo I, Guzmán M.  The CB1 receptor interacts with cereblon and drives cereblon deficiency-associated memory shortfalls EMBO Molecular Medicine,  2024;  16(4),  755 - 783
• DelaCuesta-Barrutia J, Martínez-Peula O, Rivero G, Santas-Martín JA, Munarriz-Cuezva E, Brocos-Mosquera I, Miranda-Azpiazu P, Diez-Alarcia R, Morentin B, Honer WG, Callado LF, Erdozain AM, Ramos-Miguel A.  Effect of antipsychotic drugs on group II metabotropic glutamate receptor expression andepigenetic control in postmortem brains of schizophrenia subjects Translational Psychiatry,  2024;  14(1):113
• Jones AA, Ramos-Miguel A, Gicas KM, Petyuk VA, Leurgans SE, De Jager PL, Schneider JA, Bennett DA, Honer WG, Casaletto KB.  A multilayer network analysis of Alzheimer's disease pathogenesis: Roles for p-tau, synaptic peptides, and physical activity Alzheimer's & Dementia (in press),  2024
• Kossatz E, Diez-Alarcia R, Gaitonde SA, Ramon-Duaso C, Stepniewski TM,Aranda-Garcia D, Muneta-Arrate I, Tepaz E, Saen-Oon S, Soliva R, Shahraki A,Moreira D, Brea J, Loza MI, de la Torre R, Kolb P, Bouvier M, Meana JJ, Robledo P, Selent J.  G protein-specific mechanisms in the serotonin 5-HT2A receptor regulate psychosis-related effects and memory deficits Nature Communications,  2024;  15(1):4307
• Lorca C, Fernández-Rhodes M, Sánchez Milán JA, Mulet M, Elortza F, Ramos- Miguel A, Callado LF, Meana JJ, Mur M, Batalla I, Vilella E, Serra A, Gallart-Palau X.  Next-Generation Proteomics of Brain Extracellular Vesicles in Schizophrenia Provide New Clues on the Altered Molecular Connectome Biomedicines,  2024;  12(1):129
• Martínez-Peula O, Morentin B, Callado LF, Meana JJ, Rivero G, Ramos-Miguel A.  Permissive epigenetic regulatory mechanisms at the histone level are enhanced in postmortem dorsolateral prefrontal cortex of individuals with schizophrenia Journal of Psychiatry & Neuroscience,  2024;  49(1),  E35 - E44
• Martínez-Peula O, Morentin B, Callado LF, Meana JJ, Rivero G, Ramos-Miguel A.  Permissive epigenetic regulatory mechanisms at the histone level are enhanced inpostmortem dorsolateral prefrontal cortex of individuals with schizophrenia Journal of Psychiatry and Neuroscience,  2024;  49(1),  E35 - E44
• Mudyanselage AW, Wijamunige BC, Kocoń A, Turner R, McLean D, Morentin B,Callado LF, Carter WG.  Alcohol Triggers the Accumulation of Oxidatively DamagedProteins in Neuronal Cells and Tissues Antioxidants (Basel),  2024;  13(5):580
• Munarriz-Cuezva E, Meana JJ.  Poly (I:C)-induced maternal immune activation generates impairment of reversal learning performance in offspring Journal of Neurochemistry (in press),  2024
• Muneta-Arrate I, Miranda-Azpiazu P, Horrillo I, Diez-Alarcia R, Meana JJ.  Ligand bias and inverse agonism on 5-HT2A receptor-mediated modulation of G protein activity in post-mortem human brain British Journal of Pharmacology,  2024;  (in press)
• Recio-Barbero M, Cabezas-Garduño J, Varona J, Ruiz-Irastorza G, Horrillo I, Meana JJ, Santos-Zorrozúa B, Segarra R.  Clinical Predictors of Mood Disorders and Prevalence of europsychiatric Symptoms in Patients with Systemic Lupus Erythematosus Journal of Clinical Medicine,  2024;  13(18):5423
• Riga MS, Pérez-Fernández M, Miquel-Rio L, Paz V, Campa L, Martínez-Losa M, Esteban FJ, Callado LF, Meana J, Artigas F, Bortolozzi A, Álvarez-Dolado M.  Scn1a haploinsufficiency in the prefrontal cortex engages to cognitive impairment and depressive phenotype Brain,  2024;  awae167 (in press)
• Sancho-Alonso M, Sarriés-Serrano U, Miquel-Rio L, Yanes Castilla C, Paz V, Meana JJ, Perello M, Bortolozzi A.  New insights into the effects of serotonin on Parkinson's disease and depression through its role in the gastrointestinal tract Spanish Journal of Psychiatry and Mental Health,  2024;  S2950-2853(24)00039-5 (in press)
• Villa M, Martínez-Vega M, Silva L, Muneta-Arrate I, Gómez-Soria A, Muguruza C, Del Pozo A, de Hoz-Rivera M, Romero A, Callado LF, Casarejos MJ, Martínez- Orgado J.  Effects of cannabidiol in post-stroke mood disorders in neonatal rats Pediatric Research,  2024;  95(7),  1783 - 1790
• Wright SC, Avet C, Gaitonde SA, Muneta-Arrate I, Le Gouill C, Hogue M, Breton B, Koutsilieri S, Diez-Alarcia R, Héroux M, Lauschke VM, Bouvier M.  Conformation- and activation-based BRET sensors differentially report on GPCR-G protein coupling Science Signaling,  2024;  17(841):eadi4747
• Zhu B, Ainsworth RI, Wang Z, Liu Z, Sierra S, Deng C, Callado LF, Meana JJ, Wang W, Lu C, González-Maeso J.  Antipsychotic-induced epigenomic reorganization in frontal cortex of individuals with schizophrenia Elife,  2024;  12:RP92393
• Fernández-Rhodes M, Lorca C, Lisa J, Batalla I, Ramos-Miguel A, Gallart-Palau X, Serra A.  New Origins of Yeast, Plant and Bacterial-Derived Extracellular Vesicles to Expand and Advance Compound Delivery International Journal of Molecular Sciences,  2024;  25(13):7151
• Ardanaz CG, de la Cruz A, Minhas PS, Hernández-Martín N, Pozo MÁ, Valdecantos MP, Valverde ÁM, Villa-Valverde P, Elizalde-Horcada M, Puerta E, Ramírez MJ, Ortega JE, Urbiola A, Ederra C, Ariz M, Ortiz-de-Solórzano C, Fernández-Irigoyen J, Santamaría E, Karsenty G, Brüning JC, Solas M.  Astrocytic GLUT1 reduction paradoxically improves central and peripheral glucose homeostasis Science Advances,  2024;  10(42):eadp1115