HPLC system (LC Agilent 1260 Infinity II) for both UHPLC and HPLC applications, with a pressure range up to 600 bars and flow rates up to 10 mL/min. It is used as a preparative HPLC in combination with a fraction collector (1260 Infinity II) to carry out the fractionation of liquid extracts/samples in effect-directed analyses.