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Alexandre Manhaes Savio
[[File:Alex_profile_summer.png | frame | right | alt=My photo here | Outside]]


alexsavio__at__gmail.com
[[File:Anat_alex.png | thumb | right | alt=My MRI here | 800px | Inside]]
 
* Contact: [[Imagen:Alex email.png]]
 
* My PGP key: [[alexsavio_pgp.key]]
 
 
 
[http://www.ehu.es/ccwintco/groupware/index.php?menuaction=phpbrain.uikb.view_article&art_id=328 Material]
 
[http://www.ehu.es/ccwintco/groupware/index.php?menuaction=phpbrain.uikb.view_article&art_id=422 Seguimientos]
 
[http://www.ehu.es/ccwintco/groupware/index.php?menuaction=phpbrain.uikb.view_article&art_id=382 Pedradas]
 
[http://www.ehu.es/ccwintco/index.php/Surveys Surveys (wiki under construction)]
 
[http://www.ehu.es/ccwintco/index.php/friday_sessions Friday Sessions]
 
 
<br/>
 
== Alexandre Manhães Savio ==
 
<h3>
Studies
</h3>
 
* PhD Thesis: ''Experiments of Machine Learning for Neurodiagnosis''. Director: Prof. Manuel Graña Romay. 08/Nov/2013
: [[media:Alex-Savio-thesis final with covers.pdf | PhD thesis]]
: [[Imagen:Cover_small.png | 200px]]
: [[media:Alex_thesis_slides.pdf‎ | Dissertation slides]]
 
* January/2010 - November/2013 - PhD Student in the '''Computational Intelligence Group''' of the '''Computer Science and Artificial Intelligence department''' - University of the Basque Country. Beca de Formación de Personal Investigador del Gobierno Vasco desde Enero del 2010, renovable los 3 años siguientes.
 
* Information Engineer (October 2006) - University of the Basque Country


<br/>
<br/>


<h2>
<h3>
Education
Work Experience
</h2>
</h3>
<ul>
 
<li>
* November/2018 - present - Cloud Applications Developer in Nordcloud Deutschland GmbH, München.
Engineer in Computer Science (October 2006)
University of the Basque Country
</li>
<li>
PhD Student
Computational Intelligence Group
Computer Science and Artificial Intelligence department
</li>
</ul>


* November/2017 - present - Part-time post-doctoral researcher in the '''Nuclear Medicine Department''' of the '''Klinikum rechts der Isar - Technische Universität München'''.
* November/2017 - October/2018 - Engineer in Siemens AG, München.
* April/2017 - October/2017 - IT Architect for MaibornWolff Gmbh, München.
* October/2015 - March/2017 - Post-doctoral research in the '''Nuclear Medicine Department''' of the '''Klinikum rechts der Isar - Technische Universität München''', Ismaninger Str. 22, 81675 Munich, Germany,
:multi-modal brain PET-MRI processing and classification for detection of dementiae, collaboration with the Wrocław University of Technology. Board member of the EuroPython Society and organizer of EuroPython 2016.
* January/2015 - October/2015 - Post-doctoral researcher for the European '''ENGINE Project''' at the '''Wrocław University of Technology''', Poland.
:collaborations with the local research group, Spanish clinical staff for medical image processing projects, brain fMRI image processing, Python programmer and EuroPython 2015 organizer.
* December/2013 - December/2014 - Post-doctoral researcher at the '''Computational Intelligence Group''' of the '''Computer Science and Artificial Intelligence department''' - University of the Basque Country
:collaborations with clinical staff for medical image processing projects, brain fMRI image processing, Python programmer and EuroPython 2015 organizer.
* January/2010 - November/2013 - PhD Student in the '''Computational Intelligence Group''' of the '''Computer Science and Artificial Intelligence department''' - University of the Basque Country. 4 years pre-doctoral grant from the Basque Government.
: Brain MR image processing and application of classification algorithms for the detection of brain neuronal disorders. Testing of new multishell brain HARDI models.
* February/2008 - December/2009 - Research assistant at the '''Computational Intelligence Group''' of the '''Computer Science and Artificial Intelligence department''' - University of the Basque Country
:MR image processing and application of classification algorithms for the detection of brain neuronal disorders.
* April/2007 - January/2008 - Software Engineer in InnovaeVision, San Sebastián, Guipúzcoa, Spain.
:Java, Spring Framework, Hibernate, C/C++ in GNU/Linux, GTK 2, Cairo graphics, DirectFB
* July/2004 - April/2007 - Software Engineer in JADE Systems S.L., Zizur Mayor, Navarra, Spain.
:C/C++, C++ Borland Builder 6, GUI design, Programming language parser (ANTLR), GNU/Linux Systems administration
<br/>
<h3>
Courses
</h3>
* July 7th-11th, 2008 - AERFAI Summer School - [http://www.cvc.uab.es/aerfaiss08/ PRMA'08] - Pattern Recognition for Motion Analysis in the [http://www.cvc.uab.es/ Computer Vision Center] of the Universidad Autónoma de Barcelona.
* July 1st-12th, 2009 - Athinoula A. Martinos Center for Biomedical Imaging, Boston, MA - [http://nmr.mgh.harvard.edu/martinos/training/multimodalImaging.php Two-Week Multi-Modality Short Course]
* May 31st - June 4th, 2010 - [http://www.fmrib.ox.ac.uk/fslcourse FSL Course] organised by FMRIB, Oxford, the Martinos Center, MGH and Heidelberg & Würzburg Universities in Heidelberg, Germany.
<br/>
<h3>
Internships
</h3>
* January 24th - July 31st, 2011 - [http://www.fmrib.ox.ac.uk/ FMRIB], University of Oxford, UK with Dr. Saad Jbabdi. On ball&stick diffusion models for multishell HARDI and model selection.
<br/>
<br/>
<h2>
 
Research Areas:
== Software ==
</h2>
 
<ul>
* [https://github.com/neurita/pypes Pypes]: a Python module based on Nipype for multimodal neuro-image pre-processing.
<li>
 
MRI medical images segmentation and registration for brain functional localization
* [https://github.com/alexsavio/aizkolari#aizkolari Aizkolari tools]: a ZIP file with the repository on Sept 20th, 2013. [[Media:Aizkolari-master.zip | click here]]
</li>
 
<li>
* [https://github.com/alexsavio My github homepage]
Gesture recognition systems
 
</li>
* [https://github.com/neurita Neurita free software packages]
</ul>
 
* [http://alexsavio.github.io/ Interlines] (my blog)
 
* 19-10-12 [[Tutorial_Python_Alex_19-10-12 | Tutorial sobre Python y scikit-learn]]
 
* Copies of some software in my GitHub account:
 
'' [[Media:Visualize_volume-master.zip  | visualize_volume]]
 
'' [[Media:Oasis_aal-master.zip  | OASIS_AAL]]
 
'' [[Media:Oasis_feets-master.zip  | OASIS_feets]]
 
== Publications ==
[[Media:Alexsavio_references.bib.zip | BibTex File]]
 
[[GIC-experimental-databases | Post-processed datasets from the work done in the group.]]
 
<h3>
2017
</h3>
; Alexandre Savio, Sarah Fünger, Masoud Tahmasian, Srinivas Rachakonda, Andrei Manoliu, Christian Sorg, Timo Grimmer, Vince Calhoun, Alexander Drzezga, Valentin Riedl and Igor Yakushev
: ''Resting state networks as simultaneously measured with fMRI and PET''
: The Journal of Nuclear Medicine, First published March 2, 2017,
: doi: 10.2967/jnumed.116.185835
: http://jnm.snmjournals.org/content/early/2017/02/23/jnumed.116.185835.abstract
 
 
; Alexandre M. Savio, Michael Schutte, Manuel Graña and Igor Yakushev
: ''Pypes: Workflows for Processing Multimodal Neuroimaging Data''
: Front. Neuroinform., 11 April 2017
: doi: 10.3389/fninf.2017.00025
: https://doi.org/10.3389/fninf.2017.00025
 
 
<h3>
2016
</h3>
; Thomas Stadhouders, Alexandre Savio, Janine Diehl-Schmid, Christian Sorg, Timo Grimmer and Igor Yakushev
: ''Alterations in neurocognitive networks in dementing disorders as assessed with simultaneous PET/fMRI''
: The Journal of Nuclear Medicine, May 2016, vol. 57, supplement 2.
: http://jnm.snmjournals.org/content/57/supplement_2/237.abstract
 
<h3>
2015
</h3>
; Konrad JACKOWSKI, Alexandre MANHAES-SAVIO, Boguslaw CYGANEK
: ''Automatic segmentation of brain tumors using tensor analysis and multimodal MRI''
: XX Medical Informatics & Technologies Conference - 21-23 October 2015. Szcyrk, Poland.
 
; Ariadna Besga, Itxaso González-Ortega, Enrique Echeburúa, Alexandre Savio, Borja Ayerdi, Darya Chyzhyk, Jose LM Madrigal, Juan C. Leza, Manuel Graña, Ana González-Pinto
: ''Discrimination between Alzheimer’s Disease and Late Onset Bipolar Disorder using multivariate analysis''
: Frontiers in Aging Neuroscience. JCR 2014 - 4.000
 
; Ariadna Besga-Basterra, Darya Chyzhyk, Itxaso González-Ortega, Alexandre Savio, Borja Ayerdi, Jon Echeveste, Manuel Graña, Ana González-Pinto
: ''Eigenanatomy on fractional anisotropy imaging provides white matter anatomical features discriminating between Alzheimer’s Disease and Late Onset Bipolar Disorder''
: Current Alzheimer Research, Volume 13, Number 5, 2016. PAges 557-565. JCR (2014) 3.889 (Q1 Clin Neurol, Q2 Neurosciences), ISSN: 1875-5828 (Online), ISSN: 1567-2050 (Print)
 
; Maite Termenon, Manuel Graña, Alexandre Savio, Anton Akusok, Yoan Miche, Amaury Lendasse
: ''Brain MRI Morphological Patterns Extraction Tool based on Extreme Learning Machine and Majority Vote Classification''
: Neurocomputing (aceptado 6 de marzo) [6]
 
; Medrano M, Maiz E, Maldonado-Martín S, Arenaza L, Rodríguez-Vigil B, Ortega FB, Ruiz JR, Larrarte E, Díez I, Sarasúa A, Tobalina I, Barrenechea L, Pérez-Asenjo J, Kannengiesser S, Manhães-Savio A, Echaniz O, Labayen I
: ''The effect of a multidisciplinary intervention program on hepatic adiposity in overweight-obese children: protocol of the EFIGRO study''
: Contemporary Clinical Trials, Article accepted for publication: 21 Sep 2015, DOI: 10.1016/j.cct.2015.09.017
 
; Darya Chyzhyk, Alexandre Savio, Manuel Graña
: Computer Aided Diagnosis of Schizophrenia on resting state fMRI data by Ensembles of ELM
: Neural Networks (2015)68:23-33. DOI information: 10.1016/j.neunet.2015.04.002 JCR (2014) 2.708 ,(2013) 2.076 (Q1 CSAI, Q3 Neurosciences), ISSN: 0893-6080
 
; Alexandre Savio, Manuel Graña
: ''Local Activity Features for Computer Aided Diagnosis of Schizophrenia on resting-state fMRI''
: Neurocomputing (Q1 CSAI: 2.005) (accepted Jan 10th, 2015)
 
; G.A. Papakostas, A. Savio, M. Graña, V.G. Kaburlasos
: ''A Lattice Computing Approach to Alzheimer’s Disease Computer Assisted Diagnosis Based on MRI Data''
: Neurocomputing, Volume 150, Part A, 20 February 2015, Pages 37–42
: http://dx.doi.org/10.1016/j.neucom.2014.02.076
 
<h3>
2014
</h3>
 
; Ariadna Besga, Manuel Graña, Ana Gonzalez-Pinto, Itxaso Gonzalez-Ortega, Alexandre Savio
: ''Observation of Genotype-Phenotype interaction effects on White Matter in Alzheimer Disease and Bipolar Disorder: a randomized controlled trial''
: Neurogune 14, San Sebastián, Spain.
 
; Alexandre Savio & Manuel Graña
: ''Brain Cloud Computing: Brain image pre-processing made easy and boring''
: Neurogune 14, San Sebastián, Spain.
 
; Alexandre Savio, Darya Chyzhyk, Manuel Graña
: ''Computer Aided Diagnosis of Schizophrenia based on local-activity measures of resting-state fMRI''
: 9th International Conference, HAIS 2014, Salamanca, Spain, June 11-13, 2014.
: Proceedings, pp 1-12. DOI: 10.1007/978-3-319-07617-1_1; Print ISBN: 978-3-319-07616-4 [http://link.springer.com/chapter/10.1007%2F978-3-319-07617-1_1]
 
; Darya Chyzhyk, Alexandre Savio, Manuel Graña,
: Evolutionary ELM wrapper feature selection for Alzheimer's disease CAD on anatomical brain MRI [http://www.sciencedirect.com/science/article/pii/S0925231213010096 pdf]
: Neurocomputing, Volume 128, 27 March 2014, Pages 73-80,
: ISSN 0925-2312, http://dx.doi.org/10.1016/j.neucom.2013.01.065.
: JCR (2012) 1.634 (T1, Q2 CSAI)
 
; Rosalia Dacosta-Aguayo; Manuel Graña; Alexandre Savio; Marina Fernández-Andújar ; Tibor Auer ; Monica Millán ; Elena López-Cancio ; Cynthia Cáceres ; Nuria Bargalló ; Cesar Garrido ; Maite Barrios ; Inmaculada Clemente ; Monica Hernández ; Jose Munuera ; Antonio Dávalos ; Maria Mataró
: ''Prognostic value of changes in resting-state functional connectivity patterns in cognitive recovery after stroke: a 3T fMRI pilot study''
: Human Brain Mapping (aceptado 15 nov 2013) online [http://onlinelibrary.wiley.com/doi/10.1002/hbm.22439/abstract]
: Impact Factor: 6.878, ISI Journal Citation Reports © Ranking: 2012: 1/14 (Neuroimaging); 1/120 (Radiology Nuclear Medicine & Medical Imaging); 23/252 (Neurosciences)
 
<h3>
2013
</h3>
: [[media:Alex-Savio-thesis final with covers.pdf | PhD Thesis]] - [[media:Alex_thesis_slides.pdf‎ | Dissertation slides]]
 
; Borja Ayerdi, Alexandre Savio, Manuel Graña
: ''Meta-ensembles of classifiers for Alzheimer's disease detection using independent ROI features''
: IWINAC 2013, Part II, LNCS 7931, pp. 122-130. Springer, Heidelberg (2013)[http://link.springer.com/chapter/10.1007%2F978-3-642-38622-0_13]
: J.M. Ferrandez et al. (Eds.):
 
; Alexandre Savio, Manuel Graña
: ''An ensemble of classifiers guided by the AAL brain atlas for Alzheimer’s disease detection''
: IWANN 2013, Part II, LNCS 7903, pp. 107-114. Springer, Heidelberg (2013) [[media:Iwann13_oasis_aal_draft.pdf|draft]][http://link.springer.com/chapter/10.1007%2F978-3-642-38682-4_13]
: I. Rojas, G. Joya, and J. Cabestany (Eds.)
 
<h3>
2012
</h3>
; Alexandre Savio, Manuel Graña
: ''Deformation based feature selection for Computer Aided Diagnosis of Alzheimer’s Disease''
: Expert Systems with Applications, Available online 20 September 2012, Volume 40, Issue 5, April 2013, Pages 1619–1628 [http://dx.doi.org/10.1016/j.eswa.2012.09.009][[Media:Alexsavio_eswa12_draft.pdf | draft]] JCR (2011) 2.203 (Q1 in CSAI)
 
; Darya Chyzhyk, Alexandre Savio and Manuel Grana
: ''Evolutionary ELM wrapper feature selection for Alzheimer's disease CAD on anatomical brain MRI''
: ELM 2012
 
; Alexandre Savio, Manuel Graña
: ''Supervised classification using deformation-based features for Alzheimer's disease detection on the OASIS cross-sectional database''
: Advances in Knowledge-Based and Intelligent Information and Engineering Systems. Frontiers in Artificial Intelligence and Applications (FAIA) series, Vol. 243, pages 2191 - 2200, 2012.
: Eds: Manuel Graña, Carlos Toro, Jorge Posada, Robert J. Howlett and Lakhmi C. Jain. [[Media:Alexsavio_kes12_draft.pdf | draft]][http://dblp.uni-trier.de/db/conf/kes/kes2012.html#Savio12]
 
; S. Jbabdi, S.N. Sotiropoulos, A.M. Savio, M. Graña, T.E.J. Behrens
: ''Model-based analysis of multi-shell diffusion MR data for tractography: How to get over fitting problems''
: Magnetic Resonance in Medicine, Volume 68, Issue 6, pages 1846–1855, December 2012, DOI: 10.1002/mrm.24204 - doi: 10.1002/mrm.24204
 
;  A. Bourisly, A. Savio, M. Graña
: ''A Meta-Analysis of FMRI Biomarkers for Alzheimer's Disease''
: OHBM 2012. June 10-14, 2012 Beijing, China
 
; Darya Chyzhyk, Manuel Graña, Alexandre Savio, Josu Maiora
: ''Hybrid Dendritic Computing with Kernel-LICA applied to Alzheimer’s Disease detection in MRI''
: Neurocomputing, 2012, Volumen 75, issue 1, pp. 72-77; ISSN 0925-2312; ISI JCR (2006) 0.860, (2007) 0.865, (2008) 1.234 (2009) 1.440 (2010) 1.429
 
<h3>
2011
</h3>
 
; A. Savio, A. Bourisly, M. Graña
: ''On Current Biomarkers for Alzheimer's Disease detected by Machine Learning techniques''
: ISMRM SCIENTIFIC WORKSHOP: Neuroimaging Biomarkers of Psychiatric Disorders: What are They?. October 13-16, 2011. Montabaur, Germany
:*[[media:Alexsavio_manuel_ismrm_final.pdf | slides (PDF)]]
:*[[media:Alexsavio_prezi_ismrm.zip | slides (Prezi flash)]]
 
; M. Graña, M. Termenon, A. Savio, A. Gonzalez-Pinto, J. Echeveste, J. M. Pérez, A. Besga
: ''Computer Aided Diagnosis system for Alzheimer Disease using brain Diffusion Tensor Imaging features selected by Pearson's correlation.''
: Neuroscience letters, Volume 502, Issue 3, September 20, 2011, Pages 225-229 on line, Index of Impact JCR (2010) 2.055
 
; Alexandre Savio, Manuel Graña, Jorge Villanúa
: ''Deformation based features for Alzheimer's disease detection with linear SVM.''
: [http://hais.pwr.wroc.pl/ Hybrid Artificial Intelligence Systems, 6th International Conference (HAIS 2011)] - HAIS 2011, Part II, LNAI 6679 proceedings, p.336-343. Springer, Heidelberg (2011)
:* [[media:ASavio-HAIS-2011.pdf |draft]]
:* [[GIC-experimental-databases/OASIS_deformation_feature_vectors | Deformation features]]
 
<h3>
2010
</h3>
; Alexandre Savio, Maite García-Sebastián, Darya Chyzhyk, Carmen Hernández, Manuel Graña, Andone Sistiaga, Adolfo Lopez de Munain, Jorge Villanúa
: ''Neurocognitive disorder detection based on Feature Vectors extracted from VBM analysis of structural MRI''
: Computers in Biology and Medicine (accepted: CBM-D-10-00306R1), Impact index JCR (2009) 1.269
:* [[media:Savio-cbm-2011_draft.pdf | draft]] [http://www.ncbi.nlm.nih.gov/pubmed/21621760]
:<b>Data:</b>
:[[GIC-experimental-databases/OASIS_VBM_feature_vectors]]
:[[List of 98 OASIS females]]
 
; Alexandre Savio, Juliette Charpentier, Maite Termenón, Ann K. Shinn, Manuel Graña
: ''Neural classifiers for schizophrenia diagnostic support on diffusion imaging data''
: Neural Network World 20(7):935-949 [http://www.nnw.cz/obsahy10.html].. ISI JCR 2009: 0.475
:* [[media:slides_schizophrenia_dti_nnw.pdf | slides]]
:* [[media:schizophrenia_dti_nnw.pdf | draft]]
: Data:
::* Post-processed subjects: [http://www.ehu.es/ccwintco/files/nnw_szhizophrenia_data/nnw_schizophrenia_dti_subjects.part01.rar part 1], [http://www.ehu.es/ccwintco/files/nnw_szhizophrenia_data/nnw_schizophrenia_dti_subjects.part02.rar part 2] and [http://www.ehu.es/ccwintco/files/nnw_szhizophrenia_data/nnw_schizophrenia_dti_subjects.part03.rar part 3]
::* Correlation values: [http://www.ehu.es/ccwintco/files/nnw_szhizophrenia_data/nnw_schizophrenia_correlation_values.part1.rar part 1], [http://www.ehu.es/ccwintco/files/nnw_szhizophrenia_data/nnw_schizophrenia_correlation_values.part2.rar part 2] and [http://www.ehu.es/ccwintco/files/nnw_szhizophrenia_data/nnw_schizophrenia_correlation_values.part3.rar part 3]
::* [http://www.ehu.es/ccwintco/files/nnw_szhizophrenia_data/nnw_schizophrenia_dti_feature_masks.tar.gz Feature masks]
::* [http://www.ehu.es/ccwintco/files/nnw_szhizophrenia_data/nnw_schizophrenia_dti_feature_vectors.tar.gz Features vectors]
::* Data extracted from the [http://insight-journal.org/midas/collection/view/190?path_navigation=17 NAMIC: Brain Multimodality] database.
 
; Alexandre Savio, Maite García-Sebastián, Andone Sistiaga, Darya Chyzhyk, Esther Fernández, Fermín Moreno, Elsa Fernández, Manuel Graña, Jorge Villanúa, Adolfo López de Munain
: ''Machine Learning Approach for Myotonic Dystrophy Diagnostic Support from MRI''
: Recent Advances in Biomedical Signal Processing, 93 - 101; 2010, Bentham Science Publishers
: Juan M. Górriz, Elmar W. Lang and Javier Ramírez (Eds),
 
; Manuel Graña, Alexandre M. Savio, Maite García-Sebastián, Elsa Fernández
: ''A Lattice Computing approach for On-line fMRI analysis''
: Image and Vision Computing 28(7):1155-1161, July 2010,; http://dx.doi.org/10.1016/j.imavis.2009.10.004; ISI JCR (2008) 1.496 (2009) 1.474 (2010) 1.525
 
; Darya Chyzhyk, Maite Termenón, Alexandre Savio
: ''A Comparison of VBM Results by SPM, ICA and LICA''
: Hybrid Artificial Intelligence Systems, 5th International Conference / HAIS 2010, San Sebastián, Spain, June 23-25, 2010. Proceedings, Part II; Emilio Corchado and Manuel Graña Romay and Alexandre Manhaes Savio, LNCS 6077, Springer Verlag 2010, pp. 429-435; ISBN: 978-3-642-13802-7; [http://dx.doi.org/10.1007/978-3-642-13803-4_53 DOI 10.1007/978-3-642-13803-4_53]
 
<h3>
2009
</h3>
; Maite García-Sebastián, Alexandre Savio, Manuel Graña, Jorge Villanúa
: ''On the use of Morphometry based features for Alzheimer's Disease detection on MRI''
: Bio-Inspired Systems: Computational and Ambient Intelligence. / IWANN 2009 (Part I); Joan Cabestany, Francisco Sandoval, Alberto Prieto, Juan M. Corchado (Editors), LNCS 5517, Springer Verlag 2009, pp. 957-964; ISBN 978-3-642-02477-1; [http://portal.acm.org/citation.cfm?id=1573045 DOI 10.1007/978-3-642-02478-8_120]
:*[[Media:GarciaSebastianSavio-VBM_SPM_SVM-IWANN2009.pdf | draft]]
:<b>Data:</b>
:[[GIC-experimental-databases/OASIS_VBM_feature_vectors]]
:[[List of 98 OASIS females]]
 
; Alexandre Savio, Maite García-Sebastián, Manuel Graña, Jorge Villanúa
: ''Results of an Adaboost approach on Alzheimer's Disease detection on MRI''
: Methods and Models in Artificial and Natural Computation. / IWINAC 2009 (Part II); José Mira, José Manuel Ferrández, José R. Álvarez, Félix de la Paz, F. Javier Toledo (Editors), LNCS 5602, Springer Verlag 2009, pp. 114-123; ISBN 978-3-642-02266-1; [http://portal.acm.org/citation.cfm?id=1574369 DOI 10.1007/978-3-642-02267-8_13]
:[[Media:GarciaSebastianSavio-VBM_SPM_SVM-IWINAC2009_v2.pdf | draft]]
:<b>Data:</b>
:[[GIC-experimental-databases/OASIS_VBM_feature_vectors]]
:[[List of 98 OASIS females]]
 
; Alexandre Savio, Maite García-Sebastián, Carmen Hernández, Manuel Graña, Jorge Villanúa
: ''Classification Results of Artificial Neural Networks for Alzheimer's Disease Detection''
: Intelligent Data Engineering and Automated Learning - IDEAL 2009; LNCS 5788, Springer Verlag 2009, pp. 641-648; ISBN: 978-3-642-04393-2; [http://www.springerlink.com/content/8q670qm0g4377822/ DOI: 10.1007/978-3-642-04394-9_78]
:[[Media:GarciaSebastianSavio-VBM SPM ANN-IDEAL2009.pdf | draft]]
:<b>Data:</b>
:[[GIC-experimental-databases/OASIS_VBM_feature_vectors]]
:[[List of 98 OASIS females]]
 
<h3>
2008
</h3>
; Maite García-Sebastián, A. M. Savio, M. Graña
: ''Comments on an Evolutionary Intensity Inhomogeneity Correction Algorithm''
: [http://ieeexplore.ieee.org/xpls/abs_all.jsp?tp=&arnumber=4631363&isnumber=4630767 | link]; Proceedings CEC 2008, pp.4146-4150; ISBN 978-1-4244-1822-0
 
; Alexandre Manhaes Savio
: ''Capítulo de libro en las Actas de las II Jornadas de Inteligencia Computacional - JIC'08''
: Ramón Moreno Jiménez, Alexandre Manhaes Savio (Editors); Servicio editorial de la UPV/EHU; :ISBN 978-84-296-2316-1
:[[Media:LibroPresentacionesVerona.pdf | slides_book]]


<br/>
<br/>
<h2>
 
Research Questions:
== Projects ==
</h2>
 
<ul>
=== XXIV Premio Toribio Echeverria ===
<li>
* Alexandre Savio y Borja Ayerdi y Manuel Graña: XXIV Premio Toribio Echeverria, Brain Cloud Computing, Premio "Ideas/Proyectos Empresariales" 2014 "Empresa Asmoak" Saria [[media:2014-05-29-Los Toribio premian proyectos de tecnología computacional. Noticias de Gipuzkoa.pdf|noticias de gipuzkoa]], [[Archivo:Con-el-premio-toribio-echeverria-20140-Brain-Cloud-Computing-team.jpg|100px|thumb|right|con el premio]], [[media:2014-05-28-noticia-SPRI.pdf|noticias SPRI]]
What are each different type of brain image registration methods useful for?
 
</li>
 
<li>
=== Segundo Premio Laborde Werlinden XIII ===
How could I apply a Random Markov Field method to make a brain image registration? Isn't it related to Mutual Information?
* Alexandre Savio, Borja Ayerdi y Manuel Graña: XIII Premio Manuel Laborde Werlinden, 2013 [http://entreprenari.com/html/cast/premios/mlaborde1.htm] [[media:Diario vasco premio laborde XIII.pdf | on the local news]]
</li>
 
<li>
 
Could that be useful or better than other existing methods?
=== MICINN Imagenes Medicas ===
</li>
 
</ul>
*Investigador Principal: Manuel Graña
* Participantes:
** UPV/EHU: Darya Chyzhyk, Blanca Rosa Cases Gutierrez, Alexandre Manhaes Savio, Josu Maiora Oria, Carmen Hernandez Gomez, Pablo Gonzalez Nalda, Borja Fernandez Gauna, Aitzol Ezeiza Ramos
** Oastek: Esther Fernandez Pardavila, Jorge Alberto Villanua Bernues, Jon Echeveste Aizpurua,
** Hospital Santiago: Ariadna Besga Basterra (baja en junio 2012)
** Vicomtech: Ivan Macia Oliver, Iñigo Barandiaran Martirena, Andoni Beristain Iraola
** Ikerbasque: Amaury Lendasse
** Colaboradores Extranjeros: Dost Ongur, Ann K. Shinn, Vassilis G Kaburlasos, Ajith Abraham, Timothy E Behrens, Saad Jbabdi, Peter Sussner
* duración: 2011-2013
* Type of participation: member of the research group
 
 
=== [http://www.ehu.es/ccwintco/index.php/Proyectos#Proyecto_Saiotek_2009-2010 SAIOTEK 2009] ===
* Investigador Principal: Manuel Graña
* Acronimo SOFLIMRI
*Titulo: Desarrollo basado en software libre de técnicas morfométricas de anatomía computacional para estudio de enfermedades neurodegenerativas
*Importe de la subvención: 32000 euros
*Duracion: 2009-2010
* [[media:Memoria-adicional-SOFLIMRI.pdf|memoria adicional final]]
* Type of participation: member of the research group
 
 
* Otros proyectos del grupo [http://www.ehu.es/ccwintco/index.php/Proyectos]


<br/>
<br/>
<h2>
 
Pending Tasks:
== Research Areas ==
</h2>
* Pattern recognition applied to medical images
<ul>
* Brain medical image processing
<li>
* Gesture recognition systems
Read articles
</li>
<li>
Prepare the presentation about different brain image registration methods for the Jornadas de Inteligencia Computacional in Verona.
</li>
<li>
Search for brain atlases and report its features.
</li>
<li>
Learn to use 3DSlicer and SPM for registration.
</li>
</ul>


<br/>
<br/>
<h2>
Deadlines de congresos y trabajos pendientes:
</h2>
<ul>
<li>


</li>
== Research Questions ==
</ul>


* How does the multivariate tensor analysis work using all the deformation tensor information?
* Is there any SOM-based framework for diffusion data modelling?
* Any application of Lattice-Computing on Probabilistic Tractography?


<br/>
<br/>
<h2>
Work diary (meetings with directors):
</h2>
<ul>
<li>


</li>
== Pending Tasks ==
</ul>
* ITK, ANTS...
* OpenMP and MPI
* Multivariate Analysis
* [https://www.nmr.mgh.harvard.edu/~lazar/ Meditate]
* DTI modeling
* Process Ann's DTI dataset
* Add MRI and ML related info pages with literature reviews on this wiki.


<br/>
=== articulos de revistas en proceso de redacción ===
* rsfMRI scalar measures and CAD
* rsfMRI connectivity matrices and CAD
=== conferencias en el horno ===
== Conferences ==
'''"I love deadlines. I especially like the whooshing sound they make as they go flying by." - Douglas Adams'''


<br/>
<br/>
<h2>
Congresos y revistas objetivo:
</h2>
<ul>
<li>


</li>
'''Coming...'''
</ul>
 


<br/>
<br/>
<h2>
 
Direcciones web de interés:
 
</h2>
 
== Current readings ==
 
<h3>Books</h3>
 
* [http://www.fil.ion.ucl.ac.uk/spm/doc/books/hbf2 Human Brain Function 2nd edition] - J Ashburner, K Friston and W Penny [http://www.ehu.es/ccwintco/groupware/index.php?menuaction=phpbrain.uikb.view_article&art_id=180 PDF completo]
 
* [http://www.amazon.com/Medical-Image-Registration-Biomedical-Engineering/dp/0849300649 Medical Image Registration] - by Joseph V. Hajnal (Editor), Derek L.G. Hill (Editor), David J. Hawkes (Editor)
 
* [http://citeseer.ist.psu.edu/unser99splines.html Splines - A perfect Fit for Signal and Image Processing]
 
* [http://www.amazon.com/Insight-into-Images-Segmentation-Registration/dp/1568812175 Insight Into Images]
 
* [http://www.amazon.co.uk/Numerical-Registration-Mathematics-Scientific-Computation/dp/0198528418/ref=sr_1_1?ie=UTF8&s=books&qid=1241451652&sr=8-1 Numerical Methods for Image Registration] - [http://www2.imm.dtu.dk/itman/phdmedimreg.html]
 
  @book{mcconnell_applications_1960,
        title = {Applications of Tensor Analysis},
        isbn = {0486603733},
        publisher = {Dover Publications},
        author = {A. J. {McConnell}},
        month = jun,
        year = {1960}
        }
 
<h3>Working articles</h3>
 
* More information in my groupware articles [http://www.ehu.es/ccwintco/groupware/index.php?menuaction=phpbrain.uikb.view_article&art_id=172 Artículos Image Registration] and [http://www.ehu.es/ccwintco/groupware/index.php?menuaction=phpbrain.uikb.view_article&art_id=328 Working Diaries]


<br/>
<br/>
== Congresos y revistas objetivo ==
=== Revistas (ordenadas por factor de impacto) ===
1- [http://www3.interscience.wiley.com/journal/10005199/home Journal of Magnetic Resonance Imaging]
2- [http://www.elsevier.com/wps/find/journaldescription.cws_home/620983/description Medical Image Analysis]
3- [http://ieeexplore.ieee.org/xpl/RecentIssue.jsp?punumber=42 IEEE Transactions on Medical Imaging]
4- [http://www3.interscience.wiley.com/journal/10005196/home Magnetic Resonance in Medicine]
=== Otras revistas ===
* [http://journals.elsevier.com/10538119/neuroimage/ Neuroimage]
* [http://www.cars-int.org Computer Assisted Radiology and Surgery]
* [http://www.springer.com/biomed/neuroscience/journal/12021 Neuroinformatics]
* [http://insight-journal.org Insight Journal]
* [http://www.midasjournal.org Midas Journal]
* [http://www.biij.org Biomedical Imaging and Intervention Journal]
* [http://brain.oxfordjournals.org/ Brain]
* [http://www.springerlink.com/content/xg267307357q/?p=6be0a6dc3f7245debd0b21fc4aa7365b&pi=0 Neural Computing and Applications]
* [http://www.elsevier.com/wps/find/journaldescription.cws_home/939/description#description Expert Systems and Applications]
* [http://scitation.aip.org/EL Electronics Letters]
* [http://ieeexplore.ieee.org/xpl/RecentIssue.jsp?reload=true&punumber=10 IEEE Transactions on Biomedical Engineering]
* [http://onlinelibrary.wiley.com/journal/10.1002/%28ISSN%291522-2586 Journal of MRI]
* [http://www.elsevier.com/wps/find/journaldescription.cws_home/505627/description#description Artificial Intelligence in Medicine]
* [http://www.tandf.co.uk/journals/tf/01969722.html Cybernetics and Systems]
* [http://www.elsevier.com/wps/find/journaldescription.cws_home/506081/description Neuroscience Letters]
=== Congresos ===
* [http://www.miccai.org/ MICCAI Society]
* [http://www.biostec.org BIOSTEC]
* [http://www.ismrm.org/meetings-workshops/future-ismrm-meetings/ ISMRM]
* [http://spie.org/medical-imaging.xml SPIE Medical Imaging]
* [http://www.cars-int.org/ Computer Assisted Radiology and Surgery]
* [http://www.humanbrainmapping.org Human Brain Mapping]
* [http://www.mie2009.org Medical Informatics Europe Conference]
* [http://www.wbir2010.org WBIR] WBIR 2010
* [http://www.biomedicalimaging.org/ International Symposium on Biomedical Imaging]
* More conferences: [http://www.isi.uu.nl/Conferences/]
<br/>
== Internet Bookmarks ==
* [http://imaging.mrc-cbu.cam.ac.uk/imaging/MniTalairach CBU Imaging Wiki]
* [http://www.youtube.com/kitware Kitware Youtube Channel]
* [http://lib.bioinfo.pl BioInfoBank Library]
* [http://www.mindboggle.info MindBoggle - A Project for Human Brain Labeling]
* [[Media:SupplementaryMaterial_Klein_NeuroImage2009.pdf | Supplementary Material Document from Klein NeuroImage 2009]]
* [http://www.eigenfactor.org/ eigenfactor.org - ranking and mapping scientific knowledge]
* [http://neuro.debian.net/ Debian Neuroscience Repository]
=== Courses ===
* [http://ocw.mit.edu/OcwWeb/Health-Sciences-and-Technology/HST-583Fall-2006/CourseHome/index.htm Functional Magnetic Resonance Imaging: Data Acquisition and Analysis - MIT OpenCourseWare]
* [http://www.ehu.es/ccwintco/index.php/Direcciones_y_datos_de_inter%C3%A9s#Cursos_de_formaci.C3.B3n Cursos de formación]
* [http://matg6.uniovi.es/Master2/presentacion2.html Master en Iniciación a la Investigación en Matemáticas]
=== Databases ===
* [http://www.oasis-brains.org OASIS]
* [http://fcon_1000.projects.nitrc.org/index.html INDI - 1000 Functional Connectomes Project]
* [http://adni.loni.ucla.edu/ ADNI]
* [http://www.nitrc.org/projects/brainmap BrainMap]
* [http://rad.med.hokudai.ac.jp/research/fa/index_e.php Fractional Anisotropy Database]
* [http://insight-journal.org/midas MIDAS]
* [http://www.childmind.org/en/healthy-brain-network/abide/ ABIDE]
* [http://fcon_1000.projects.nitrc.org/indi/retro/cobre.html COBRE-Schizophrenia]
=== Research Groups ===
* [http://www.fmrib.ox.ac.uk/ Oxford Centre for Functional MRI of the Brain] - University of Oxford - JR Hospital - England
* [http://cmic.cs.ucl.ac.uk Centre of Medical Image Computing] - University College London - Gower Street - Eng. Building
* [http://dbm.neuro.uni-jena.de Structural Brain Mapping Group] - University of Jena - Thüringen - central Germany
* [https://www.rad.upenn.edu/sbia/software/index.html Section of Biomedical Image Analysis] - University of Pennsylvania
* [http://www.mpih-frankfurt.mpg.de Max Planck Institute für Hirnforschung]
* [http://image.hggm.es/ Laboratorio de Imagen Médica. Unidad de Medicina y Cirugía Experimental] - Hospital General Universitario Gregorio Marañón
* [http://www2.bic.mni.mcgill.ca/ McConnell Brain Imaging Centre (BIC) of the Montreal Neurological Institute (MNI)] - McGill University
* [http://www.na-mic.org/ National Alliance for Medical Image Computing]
* [http://www-sop.inria.fr/asclepios/ Asclepios project] - INRIA Sophia-Antipolis
* [http://www-sop.inria.fr/odyssee/en/ ODYSSEE research project-team] - INRIA Sophia-Antipolis
* [http://www.mr.ethz.ch/ Divisions of Bioimaging and MRI Technology] - University and ETH Zurich
* [http://www.bigr.nl/website/ Biomedical Imaging Group Rotterdam] - Erasmus MC - University Medical Center Rotterdam
* [http://mindhive.mit.edu/ A community portal for MIT brain research] - Massachussets Institute of Technology
* [http://www.siani.es Instituto Universitario de Sistemas Inteligentes y Aplicaciones Numéricas en Ingeniería] - ULPGC
* [http://www.fei.edu.br/~cet/ipl.html Image Processing Lab de la FEI] Sao Bernardo do Campo (SP) - Brasil
<br/>
== Utilities ==
=== Scientific Writing ===
* [[Media:How_to_write_a_good_introduction.pdf | Chapter "How to Write an Introduction" of Professor Glasman-Deal's Science Research Writing For Non-Native Speakers of English]] ( [http://www.worldscibooks.com/general/p605.html Ref.] )
* [[Media:Writing_about_methodology.pdf | Chapter "Writing about methodology" of Professor Glasman-Deal's Science Research Writing For Non-Native Speakers of English]]
* [[Media:Customize_and_improve_matlab_plots.pdf | Customise and improve Matlab plots.]]
=== Computer Settings ===
* [[como-instalar-vpn-en-ubuntu | Install Cisco VPN client on Ubuntu 8.04]]
* [[SPIE LaTEX manuscript templates and writing guidelines]]
* [http://www.cs.stir.ac.uk/~kjt/software/latex/showbst.html BibTeX Style Examples]
* [http://impressive.sourceforge.net Impressive - The stylish way of giving PDF presentations]
* Install ITK and Kitware software from sources. [http://www.itk.org/Wiki/ITK_Configuring_and_Building] [http://www.vtk.org/Wiki/Complete_Setup] (for more information ask me)
* [http://www.itk.org/Wiki/ITK_Python_Wrapping Install python wrapper on building ITK from sources.]
* [http://www.slicer.org/slicerWiki/index.php/Slicer3:Execution_Model_Documentation#Types_of_Slicer_3_Plugins Create a 3DSlicer Plugin]
* [http://davyd.livejournal.com/230629.html Sync Tomboy Notes]
* [[Pushing_references_from_JabRef_To_Lyx | Push references from JabRef to Lyx]]
* [http://neuro.debian.net/ Página de instalación de FSL en Debian]
* [[Setting up FSL to use a SunGridEngine or computing cluster]]
* [[How to install Springer LNCS Style for Lyx]]
* [http://www.oak-tree.us/blog/index.php/2009/12/02/latex-cv-part3#more-1332 Automatically Generate a List of Publications for your CV]
* [http://www.ehu.es/ccwintco/files/giclus_installation_procedure_technical_note.html Setting up a Ubuntu 10.04.1 cluster (NFS, NIS, Sun Grid Engine, FSL)] [[Media:Giclus_installation_procedure_technical_note.pdf | Giclus10.04 Installation Procedure (PDF File)]]
* [[Media:Giclus_sun_grid_engine-2010.pdf | GIC Cluster Presentation]]
* [[Media:Git for dummies.png | Git Cheat sheet for Dummies.]]
=== Image Processing ===
* [[Nomenclatura_planos_de_corte | Nomenclatura de los planos de corte en los seres vivos]]
* [http://www.na-mic.org/svn/NAMICSandBox/trunk/ NA-MIC Software Repository]
* [http://www.imagemagick.org/Usage ImageMagick Usage Examples]
* [http://www.fmrib.ox.ac.uk/fsl/fslvbm/index.html FSL VBM How to]
* [http://www.nitrc.org/projects/multimodereg BRAINSFit - Rigid Registration Tool]
* [[Statistical Parametric Mapping]]
* [http://en.wikibooks.org/wiki/SPM/Programming_intro SPM Programming Intro]
* [http://www.sph.umich.edu/~nichols/JohnsGems5.html SPM5-Specific code snippets by John Ashburner]
* [http://www.ogre3d.org/wiki/index.php/Quaternion_and_Rotation_Primer#Quaternion_Rotations A Quaternion and Rotation Primer]
* [http://www.fmrib.ox.ac.uk/fsl/fdt/index.html FMRIB's Diffusion Toolbox - FDT v2.0]
* [http://www.na-mic.org/Wiki/index.php/Slicer3.2:Training 3D Slicer User Documentation]
* [http://www.sph.sc.edu/comd/rorden/workshop/fsl/dti/index.html Short introduction to DTI analysis]
* [http://www.nitrc.org/projects/art/ Automatic Registration Toolbox (ART)]
* [http://www.ogre3d.org/wiki/index.php/Quaternion_and_Rotation_Primer#Quaternion_Rotations A Quaternion and Rotation Primer]
* [http://www.picsl.upenn.edu/ANTS/ Advanced Open Source Tools for Normalization and Neuroanatomy (SyN nonlinear registration algorithm)]
* [http://www.itksnap.org Semi-Automatic and Manual Segmentation of 3D Volumes]
* [http://www.parallelpython.com Parallel Python for parallel processing]
* [http://www.cs.ucl.ac.uk/staff/g.ridgway/masking/ Mask creation software for VBM analyses for SPM8]
* [http://afni.nimh.nih.gov/afni/community/board/read.php?f=1&i=2066&t=1278&v=f Preprocessing steps for SPM Analyze images to use them on FSL]
* [http://www.fmrimethods.org/index.php/Main_Page fMRI methods]
* [http://www.fmrib.ox.ac.uk/Members/karla/lectures-and-teaching-material Ms. Karla Miller's lecture presentations]
* [[media:fdt.pdf | FMRIB Diffusion Toolbox]]
=== Pattern Recognition ===
* [[alexsavio_scripts | My scripts]]
* [[Wiki Weka | Weka How Tos]]
* [[Matrices de confusión y otros valores estadísticos]]
* [http://www.csie.ntu.edu.tw/~cjlin/libsvm/ LIBSVM - A library for Support Vector Machines]
* [http://www.support-vector-machines.org/SVM_soft.html Spider SVM]
* [http://www.vias.org/tmdatanaleng/cc_scaling.html Teach Me Data Analysis (Range scaling)]
* [http://page.mi.fu-berlin.de/rojas/neural/index.html.html Neural Networks - A Systematic Introduction]
* [[Presentaciones-informes-software-veganzones | Some interesting presentations]]
* [http://www.siam.org/meetings/op08/invited.php Invited speakers for SIAM Conference on Optimization] (Modersitzki presentation on image registration)
=== Real World ===
* [[Media:Useful things to know about the PhD.pdf | Some useful hints to know about the PhD]]
* [http://www.youtube.com/watch?v=XViCOAu6UC0 What the Simpsons think about graduate students!!]
* [[Media:InsightOpenScience.pdf | Presentación de Luis Ibañez sobre el sin sentido del entorno de "ciencia abierta" en la que trabajamos.]] ( [http://www.kitware.com/company/team/ibanez.html Página personal de Luis Ibañez en Kitware] )
* [https://www-304.ibm.com/jct09002c/university/scholars/collaborativeresearch/results.html Collaborative Research Initiatives]
* [[Media:OpenCollaborationPrinciples_2005.pdf | Principios de colaboración abierta en la investigación (2005)]]
* [http://boloniaiifordummies.blogspot.com/2008/11/preguntas-y-respuestas.html Preguntas y respuestas sobre la situación Ingeniería Informática - Tratado de Bolonia, con referencias.]
* [http://www.acceleratingfuture.com/michael/works/tenreasons.htm 10 Reasons]
* [http://www.ehu.es/ccwintco/index.php/Usuario:Natafresa#Visita_al_Instituto_Nacional_de_Pesquisas_Espaciais_.28INPE.29.2C_Sao_Jos.C3.A9_Dos_Campos_.28Brasil.29.2C_Enero_2009 Visita al Instituto Nacional de Pesquisas Espaciais (INPE), Sao José Dos Campos (Brasil), Enero 2009]
* [[fotos-veganzones | Miguel's Photo gallery]]
<br/>
== Estado burocrático de la tesis ==
; Director: Manuel Graña
; Trabajo de investigación aprobado.
; [[Media:Contratos_PIC_2008-2009.pdf | Contratos durante los años 2008 y 2009]]
; Beca de Formación de Personal Investigador del Gobierno Vasco para los años 2010, 2011, 2012 y 2013 (todas las renovaciones ya han sido concedidas).

Revisión actual - 13:37 4 feb 2019

My photo here
Outside
My MRI here
Inside
  • Contact: Alex email.png


Material

Seguimientos

Pedradas

Surveys (wiki under construction)

Friday Sessions



Alexandre Manhães Savio

Studies

  • PhD Thesis: Experiments of Machine Learning for Neurodiagnosis. Director: Prof. Manuel Graña Romay. 08/Nov/2013
PhD thesis
Cover small.png
Dissertation slides
  • January/2010 - November/2013 - PhD Student in the Computational Intelligence Group of the Computer Science and Artificial Intelligence department - University of the Basque Country. Beca de Formación de Personal Investigador del Gobierno Vasco desde Enero del 2010, renovable los 3 años siguientes.
  • Information Engineer (October 2006) - University of the Basque Country


Work Experience

  • November/2018 - present - Cloud Applications Developer in Nordcloud Deutschland GmbH, München.
  • November/2017 - present - Part-time post-doctoral researcher in the Nuclear Medicine Department of the Klinikum rechts der Isar - Technische Universität München.
  • November/2017 - October/2018 - Engineer in Siemens AG, München.
  • April/2017 - October/2017 - IT Architect for MaibornWolff Gmbh, München.
  • October/2015 - March/2017 - Post-doctoral research in the Nuclear Medicine Department of the Klinikum rechts der Isar - Technische Universität München, Ismaninger Str. 22, 81675 Munich, Germany,
multi-modal brain PET-MRI processing and classification for detection of dementiae, collaboration with the Wrocław University of Technology. Board member of the EuroPython Society and organizer of EuroPython 2016.
  • January/2015 - October/2015 - Post-doctoral researcher for the European ENGINE Project at the Wrocław University of Technology, Poland.
collaborations with the local research group, Spanish clinical staff for medical image processing projects, brain fMRI image processing, Python programmer and EuroPython 2015 organizer.
  • December/2013 - December/2014 - Post-doctoral researcher at the Computational Intelligence Group of the Computer Science and Artificial Intelligence department - University of the Basque Country
collaborations with clinical staff for medical image processing projects, brain fMRI image processing, Python programmer and EuroPython 2015 organizer.
  • January/2010 - November/2013 - PhD Student in the Computational Intelligence Group of the Computer Science and Artificial Intelligence department - University of the Basque Country. 4 years pre-doctoral grant from the Basque Government.
Brain MR image processing and application of classification algorithms for the detection of brain neuronal disorders. Testing of new multishell brain HARDI models.
  • February/2008 - December/2009 - Research assistant at the Computational Intelligence Group of the Computer Science and Artificial Intelligence department - University of the Basque Country
MR image processing and application of classification algorithms for the detection of brain neuronal disorders.
  • April/2007 - January/2008 - Software Engineer in InnovaeVision, San Sebastián, Guipúzcoa, Spain.
Java, Spring Framework, Hibernate, C/C++ in GNU/Linux, GTK 2, Cairo graphics, DirectFB
  • July/2004 - April/2007 - Software Engineer in JADE Systems S.L., Zizur Mayor, Navarra, Spain.
C/C++, C++ Borland Builder 6, GUI design, Programming language parser (ANTLR), GNU/Linux Systems administration


Courses

  • July 7th-11th, 2008 - AERFAI Summer School - PRMA'08 - Pattern Recognition for Motion Analysis in the Computer Vision Center of the Universidad Autónoma de Barcelona.
  • May 31st - June 4th, 2010 - FSL Course organised by FMRIB, Oxford, the Martinos Center, MGH and Heidelberg & Würzburg Universities in Heidelberg, Germany.


Internships

  • January 24th - July 31st, 2011 - FMRIB, University of Oxford, UK with Dr. Saad Jbabdi. On ball&stick diffusion models for multishell HARDI and model selection.


Software

  • Pypes: a Python module based on Nipype for multimodal neuro-image pre-processing.
  • Copies of some software in my GitHub account:

visualize_volume

OASIS_AAL

OASIS_feets

Publications

BibTex File

Post-processed datasets from the work done in the group.

2017

Alexandre Savio, Sarah Fünger, Masoud Tahmasian, Srinivas Rachakonda, Andrei Manoliu, Christian Sorg, Timo Grimmer, Vince Calhoun, Alexander Drzezga, Valentin Riedl and Igor Yakushev
Resting state networks as simultaneously measured with fMRI and PET
The Journal of Nuclear Medicine, First published March 2, 2017,
doi: 10.2967/jnumed.116.185835
http://jnm.snmjournals.org/content/early/2017/02/23/jnumed.116.185835.abstract


Alexandre M. Savio, Michael Schutte, Manuel Graña and Igor Yakushev
Pypes: Workflows for Processing Multimodal Neuroimaging Data
Front. Neuroinform., 11 April 2017
doi: 10.3389/fninf.2017.00025
https://doi.org/10.3389/fninf.2017.00025


2016

Thomas Stadhouders, Alexandre Savio, Janine Diehl-Schmid, Christian Sorg, Timo Grimmer and Igor Yakushev
Alterations in neurocognitive networks in dementing disorders as assessed with simultaneous PET/fMRI
The Journal of Nuclear Medicine, May 2016, vol. 57, supplement 2.
http://jnm.snmjournals.org/content/57/supplement_2/237.abstract

2015

Konrad JACKOWSKI, Alexandre MANHAES-SAVIO, Boguslaw CYGANEK
Automatic segmentation of brain tumors using tensor analysis and multimodal MRI
XX Medical Informatics & Technologies Conference - 21-23 October 2015. Szcyrk, Poland.
Ariadna Besga, Itxaso González-Ortega, Enrique Echeburúa, Alexandre Savio, Borja Ayerdi, Darya Chyzhyk, Jose LM Madrigal, Juan C. Leza, Manuel Graña, Ana González-Pinto
Discrimination between Alzheimer’s Disease and Late Onset Bipolar Disorder using multivariate analysis
Frontiers in Aging Neuroscience. JCR 2014 - 4.000
Ariadna Besga-Basterra, Darya Chyzhyk, Itxaso González-Ortega, Alexandre Savio, Borja Ayerdi, Jon Echeveste, Manuel Graña, Ana González-Pinto
Eigenanatomy on fractional anisotropy imaging provides white matter anatomical features discriminating between Alzheimer’s Disease and Late Onset Bipolar Disorder
Current Alzheimer Research, Volume 13, Number 5, 2016. PAges 557-565. JCR (2014) 3.889 (Q1 Clin Neurol, Q2 Neurosciences), ISSN: 1875-5828 (Online), ISSN: 1567-2050 (Print)
Maite Termenon, Manuel Graña, Alexandre Savio, Anton Akusok, Yoan Miche, Amaury Lendasse
Brain MRI Morphological Patterns Extraction Tool based on Extreme Learning Machine and Majority Vote Classification
Neurocomputing (aceptado 6 de marzo) [6]
Medrano M, Maiz E, Maldonado-Martín S, Arenaza L, Rodríguez-Vigil B, Ortega FB, Ruiz JR, Larrarte E, Díez I, Sarasúa A, Tobalina I, Barrenechea L, Pérez-Asenjo J, Kannengiesser S, Manhães-Savio A, Echaniz O, Labayen I
The effect of a multidisciplinary intervention program on hepatic adiposity in overweight-obese children: protocol of the EFIGRO study
Contemporary Clinical Trials, Article accepted for publication: 21 Sep 2015, DOI: 10.1016/j.cct.2015.09.017
Darya Chyzhyk, Alexandre Savio, Manuel Graña
Computer Aided Diagnosis of Schizophrenia on resting state fMRI data by Ensembles of ELM
Neural Networks (2015)68:23-33. DOI information: 10.1016/j.neunet.2015.04.002 JCR (2014) 2.708 ,(2013) 2.076 (Q1 CSAI, Q3 Neurosciences), ISSN: 0893-6080
Alexandre Savio, Manuel Graña
Local Activity Features for Computer Aided Diagnosis of Schizophrenia on resting-state fMRI
Neurocomputing (Q1 CSAI: 2.005) (accepted Jan 10th, 2015)
G.A. Papakostas, A. Savio, M. Graña, V.G. Kaburlasos
A Lattice Computing Approach to Alzheimer’s Disease Computer Assisted Diagnosis Based on MRI Data
Neurocomputing, Volume 150, Part A, 20 February 2015, Pages 37–42
http://dx.doi.org/10.1016/j.neucom.2014.02.076

2014

Ariadna Besga, Manuel Graña, Ana Gonzalez-Pinto, Itxaso Gonzalez-Ortega, Alexandre Savio
Observation of Genotype-Phenotype interaction effects on White Matter in Alzheimer Disease and Bipolar Disorder: a randomized controlled trial
Neurogune 14, San Sebastián, Spain.
Alexandre Savio & Manuel Graña
Brain Cloud Computing: Brain image pre-processing made easy and boring
Neurogune 14, San Sebastián, Spain.
Alexandre Savio, Darya Chyzhyk, Manuel Graña
Computer Aided Diagnosis of Schizophrenia based on local-activity measures of resting-state fMRI
9th International Conference, HAIS 2014, Salamanca, Spain, June 11-13, 2014.
Proceedings, pp 1-12. DOI: 10.1007/978-3-319-07617-1_1; Print ISBN: 978-3-319-07616-4 [1]
Darya Chyzhyk, Alexandre Savio, Manuel Graña,
Evolutionary ELM wrapper feature selection for Alzheimer's disease CAD on anatomical brain MRI pdf
Neurocomputing, Volume 128, 27 March 2014, Pages 73-80,
ISSN 0925-2312, http://dx.doi.org/10.1016/j.neucom.2013.01.065.
JCR (2012) 1.634 (T1, Q2 CSAI)
Rosalia Dacosta-Aguayo; Manuel Graña; Alexandre Savio; Marina Fernández-Andújar ; Tibor Auer ; Monica Millán ; Elena López-Cancio ; Cynthia Cáceres ; Nuria Bargalló ; Cesar Garrido ; Maite Barrios ; Inmaculada Clemente ; Monica Hernández ; Jose Munuera ; Antonio Dávalos ; Maria Mataró
Prognostic value of changes in resting-state functional connectivity patterns in cognitive recovery after stroke: a 3T fMRI pilot study
Human Brain Mapping (aceptado 15 nov 2013) online [2]
Impact Factor: 6.878, ISI Journal Citation Reports © Ranking: 2012: 1/14 (Neuroimaging); 1/120 (Radiology Nuclear Medicine & Medical Imaging); 23/252 (Neurosciences)

2013

PhD Thesis - Dissertation slides
Borja Ayerdi, Alexandre Savio, Manuel Graña
Meta-ensembles of classifiers for Alzheimer's disease detection using independent ROI features
IWINAC 2013, Part II, LNCS 7931, pp. 122-130. Springer, Heidelberg (2013)[3]
J.M. Ferrandez et al. (Eds.):
Alexandre Savio, Manuel Graña
An ensemble of classifiers guided by the AAL brain atlas for Alzheimer’s disease detection
IWANN 2013, Part II, LNCS 7903, pp. 107-114. Springer, Heidelberg (2013) draft[4]
I. Rojas, G. Joya, and J. Cabestany (Eds.)

2012

Alexandre Savio, Manuel Graña
Deformation based feature selection for Computer Aided Diagnosis of Alzheimer’s Disease
Expert Systems with Applications, Available online 20 September 2012, Volume 40, Issue 5, April 2013, Pages 1619–1628 [5] draft JCR (2011) 2.203 (Q1 in CSAI)
Darya Chyzhyk, Alexandre Savio and Manuel Grana
Evolutionary ELM wrapper feature selection for Alzheimer's disease CAD on anatomical brain MRI
ELM 2012
Alexandre Savio, Manuel Graña
Supervised classification using deformation-based features for Alzheimer's disease detection on the OASIS cross-sectional database
Advances in Knowledge-Based and Intelligent Information and Engineering Systems. Frontiers in Artificial Intelligence and Applications (FAIA) series, Vol. 243, pages 2191 - 2200, 2012.
Eds: Manuel Graña, Carlos Toro, Jorge Posada, Robert J. Howlett and Lakhmi C. Jain. draft[6]
S. Jbabdi, S.N. Sotiropoulos, A.M. Savio, M. Graña, T.E.J. Behrens
Model-based analysis of multi-shell diffusion MR data for tractography: How to get over fitting problems
Magnetic Resonance in Medicine, Volume 68, Issue 6, pages 1846–1855, December 2012, DOI: 10.1002/mrm.24204 - doi: 10.1002/mrm.24204
A. Bourisly, A. Savio, M. Graña
A Meta-Analysis of FMRI Biomarkers for Alzheimer's Disease
OHBM 2012. June 10-14, 2012 Beijing, China
Darya Chyzhyk, Manuel Graña, Alexandre Savio, Josu Maiora
Hybrid Dendritic Computing with Kernel-LICA applied to Alzheimer’s Disease detection in MRI
Neurocomputing, 2012, Volumen 75, issue 1, pp. 72-77; ISSN 0925-2312; ISI JCR (2006) 0.860, (2007) 0.865, (2008) 1.234 (2009) 1.440 (2010) 1.429

2011

A. Savio, A. Bourisly, M. Graña
On Current Biomarkers for Alzheimer's Disease detected by Machine Learning techniques
ISMRM SCIENTIFIC WORKSHOP: Neuroimaging Biomarkers of Psychiatric Disorders: What are They?. October 13-16, 2011. Montabaur, Germany
M. Graña, M. Termenon, A. Savio, A. Gonzalez-Pinto, J. Echeveste, J. M. Pérez, A. Besga
Computer Aided Diagnosis system for Alzheimer Disease using brain Diffusion Tensor Imaging features selected by Pearson's correlation.
Neuroscience letters, Volume 502, Issue 3, September 20, 2011, Pages 225-229 on line, Index of Impact JCR (2010) 2.055
Alexandre Savio, Manuel Graña, Jorge Villanúa
Deformation based features for Alzheimer's disease detection with linear SVM.
Hybrid Artificial Intelligence Systems, 6th International Conference (HAIS 2011) - HAIS 2011, Part II, LNAI 6679 proceedings, p.336-343. Springer, Heidelberg (2011)

2010

Alexandre Savio, Maite García-Sebastián, Darya Chyzhyk, Carmen Hernández, Manuel Graña, Andone Sistiaga, Adolfo Lopez de Munain, Jorge Villanúa
Neurocognitive disorder detection based on Feature Vectors extracted from VBM analysis of structural MRI
Computers in Biology and Medicine (accepted: CBM-D-10-00306R1), Impact index JCR (2009) 1.269
Data:
GIC-experimental-databases/OASIS_VBM_feature_vectors
List of 98 OASIS females
Alexandre Savio, Juliette Charpentier, Maite Termenón, Ann K. Shinn, Manuel Graña
Neural classifiers for schizophrenia diagnostic support on diffusion imaging data
Neural Network World 20(7):935-949 [8].. ISI JCR 2009: 0.475
Data:
Alexandre Savio, Maite García-Sebastián, Andone Sistiaga, Darya Chyzhyk, Esther Fernández, Fermín Moreno, Elsa Fernández, Manuel Graña, Jorge Villanúa, Adolfo López de Munain
Machine Learning Approach for Myotonic Dystrophy Diagnostic Support from MRI
Recent Advances in Biomedical Signal Processing, 93 - 101; 2010, Bentham Science Publishers
Juan M. Górriz, Elmar W. Lang and Javier Ramírez (Eds),
Manuel Graña, Alexandre M. Savio, Maite García-Sebastián, Elsa Fernández
A Lattice Computing approach for On-line fMRI analysis
Image and Vision Computing 28(7):1155-1161, July 2010,; http://dx.doi.org/10.1016/j.imavis.2009.10.004; ISI JCR (2008) 1.496 (2009) 1.474 (2010) 1.525
Darya Chyzhyk, Maite Termenón, Alexandre Savio
A Comparison of VBM Results by SPM, ICA and LICA
Hybrid Artificial Intelligence Systems, 5th International Conference / HAIS 2010, San Sebastián, Spain, June 23-25, 2010. Proceedings, Part II; Emilio Corchado and Manuel Graña Romay and Alexandre Manhaes Savio, LNCS 6077, Springer Verlag 2010, pp. 429-435; ISBN: 978-3-642-13802-7; DOI 10.1007/978-3-642-13803-4_53

2009

Maite García-Sebastián, Alexandre Savio, Manuel Graña, Jorge Villanúa
On the use of Morphometry based features for Alzheimer's Disease detection on MRI
Bio-Inspired Systems: Computational and Ambient Intelligence. / IWANN 2009 (Part I); Joan Cabestany, Francisco Sandoval, Alberto Prieto, Juan M. Corchado (Editors), LNCS 5517, Springer Verlag 2009, pp. 957-964; ISBN 978-3-642-02477-1; DOI 10.1007/978-3-642-02478-8_120
Data:
GIC-experimental-databases/OASIS_VBM_feature_vectors
List of 98 OASIS females
Alexandre Savio, Maite García-Sebastián, Manuel Graña, Jorge Villanúa
Results of an Adaboost approach on Alzheimer's Disease detection on MRI
Methods and Models in Artificial and Natural Computation. / IWINAC 2009 (Part II); José Mira, José Manuel Ferrández, José R. Álvarez, Félix de la Paz, F. Javier Toledo (Editors), LNCS 5602, Springer Verlag 2009, pp. 114-123; ISBN 978-3-642-02266-1; DOI 10.1007/978-3-642-02267-8_13
draft
Data:
GIC-experimental-databases/OASIS_VBM_feature_vectors
List of 98 OASIS females
Alexandre Savio, Maite García-Sebastián, Carmen Hernández, Manuel Graña, Jorge Villanúa
Classification Results of Artificial Neural Networks for Alzheimer's Disease Detection
Intelligent Data Engineering and Automated Learning - IDEAL 2009; LNCS 5788, Springer Verlag 2009, pp. 641-648; ISBN: 978-3-642-04393-2; DOI: 10.1007/978-3-642-04394-9_78
draft
Data:
GIC-experimental-databases/OASIS_VBM_feature_vectors
List of 98 OASIS females

2008

Maite García-Sebastián, A. M. Savio, M. Graña
Comments on an Evolutionary Intensity Inhomogeneity Correction Algorithm
| link; Proceedings CEC 2008, pp.4146-4150; ISBN 978-1-4244-1822-0
Alexandre Manhaes Savio
Capítulo de libro en las Actas de las II Jornadas de Inteligencia Computacional - JIC'08
Ramón Moreno Jiménez, Alexandre Manhaes Savio (Editors); Servicio editorial de la UPV/EHU; :ISBN 978-84-296-2316-1
slides_book


Projects

XXIV Premio Toribio Echeverria

* Alexandre Savio y Borja Ayerdi y Manuel Graña: XXIV Premio Toribio Echeverria, Brain Cloud Computing, Premio "Ideas/Proyectos Empresariales" 2014 "Empresa Asmoak" Saria noticias de gipuzkoa,

con el premio

, noticias SPRI


Segundo Premio Laborde Werlinden XIII

  • Alexandre Savio, Borja Ayerdi y Manuel Graña: XIII Premio Manuel Laborde Werlinden, 2013 [9] on the local news


MICINN Imagenes Medicas

  • Investigador Principal: Manuel Graña
  • Participantes:
    • UPV/EHU: Darya Chyzhyk, Blanca Rosa Cases Gutierrez, Alexandre Manhaes Savio, Josu Maiora Oria, Carmen Hernandez Gomez, Pablo Gonzalez Nalda, Borja Fernandez Gauna, Aitzol Ezeiza Ramos
    • Oastek: Esther Fernandez Pardavila, Jorge Alberto Villanua Bernues, Jon Echeveste Aizpurua,
    • Hospital Santiago: Ariadna Besga Basterra (baja en junio 2012)
    • Vicomtech: Ivan Macia Oliver, Iñigo Barandiaran Martirena, Andoni Beristain Iraola
    • Ikerbasque: Amaury Lendasse
    • Colaboradores Extranjeros: Dost Ongur, Ann K. Shinn, Vassilis G Kaburlasos, Ajith Abraham, Timothy E Behrens, Saad Jbabdi, Peter Sussner
  • duración: 2011-2013
  • Type of participation: member of the research group


SAIOTEK 2009

  • Investigador Principal: Manuel Graña
  • Acronimo SOFLIMRI
  • Titulo: Desarrollo basado en software libre de técnicas morfométricas de anatomía computacional para estudio de enfermedades neurodegenerativas
  • Importe de la subvención: 32000 euros
  • Duracion: 2009-2010
  • memoria adicional final
  • Type of participation: member of the research group


  • Otros proyectos del grupo [10]


Research Areas

  • Pattern recognition applied to medical images
  • Brain medical image processing
  • Gesture recognition systems


Research Questions

  • How does the multivariate tensor analysis work using all the deformation tensor information?
  • Is there any SOM-based framework for diffusion data modelling?
  • Any application of Lattice-Computing on Probabilistic Tractography?


Pending Tasks

  • ITK, ANTS...
  • OpenMP and MPI
  • Multivariate Analysis
  • Meditate
  • DTI modeling
  • Process Ann's DTI dataset
  • Add MRI and ML related info pages with literature reviews on this wiki.


articulos de revistas en proceso de redacción

  • rsfMRI scalar measures and CAD
  • rsfMRI connectivity matrices and CAD

conferencias en el horno

Conferences

"I love deadlines. I especially like the whooshing sound they make as they go flying by." - Douglas Adams


Coming...




Current readings

Books

  @book{mcconnell_applications_1960,
        title = {Applications of Tensor Analysis},
        isbn = {0486603733},
        publisher = {Dover Publications},
        author = {A. J. {McConnell}},
        month = jun,
        year = {1960}
       }

Working articles


Congresos y revistas objetivo

Revistas (ordenadas por factor de impacto)

1- Journal of Magnetic Resonance Imaging

2- Medical Image Analysis

3- IEEE Transactions on Medical Imaging

4- Magnetic Resonance in Medicine

Otras revistas

Congresos

  • More conferences: [12]


Internet Bookmarks

Courses

Databases

Research Groups


Utilities

Scientific Writing

Computer Settings

  • Install ITK and Kitware software from sources. [13] [14] (for more information ask me)

Image Processing

Pattern Recognition

Real World


Estado burocrático de la tesis

Director
Manuel Graña
Trabajo de investigación aprobado.
Contratos durante los años 2008 y 2009
Beca de Formación de Personal Investigador del Gobierno Vasco para los años 2010, 2011, 2012 y 2013 (todas las renovaciones ya han sido concedidas).