Self-powered microfluidics is an emerging field of special interest in the field of rapid analysis. In this line we are witnessing the development of paper and capillary driven microfluidics. A new type of system in on the rise, degas driven flow microfluidics. We report the development of disposable place and play (PnP) micropumps with high flow. We show the capacity of these micropumps to drive flow inside microchannels for more than 30 minutes. The PnP-micropumps were assembled with simple low cost polymeric microfluidic strips made of machined polymer sheets,. Additionally, a numerical preliminary study is performed to resolve and analyse the flow of interest and so to demonstrate its use, in further microfluidics studies, as a designing and/or optimization tool. Initial numerical results show a good correspondence with the experimental data and suggest its applicability for this purpose.