GENERAL PROTEOMICS SERVICE

Equipment: Liquid Chromatography-Mass Spectrometry

Brand: Thermo Scientific

Model: EASY nLC-1200 System (LC) and Orbitrap Exploris 480 (MS)

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Description: The EASY-nLC 1200 UHPLC system offers maximum performance for nano LC MS/MS applications and is connected to the mass spectrometer via the NanoSpray Flex NG ion source. The Orbitrap Exploris 480 is a high-end compact quadrupole Orbitrap mass spectrometer. It is equipped with the FAIMS Pro interface. This instrument is used for the most demanding proteomic analyses.

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Applications:

• Identification and quantification of proteins:
  • Highly complex samples.
  • Labeled and label-free quantification approaches.
  • Low amount (single cell).
  • Data Dependent (DDA) and Data Independent (DIA) acquisition modes.
• Analysis of Post-Translational Modifications:
  • Phosphorylation.
  • Ubiquitination.
• Structural proteomics based on cross-linking mass spectrometry.
• Interaction proteomics: analysis of protein interactions across the entire proteome.

If these applications are not suitable for your project, please do not hesitate to contact us. We will try to adapt our current methods or develop new ones to meet your needs.

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Responsible(s): Kerman Aloria

Location: Marya Goyri Biotechnology Center

Sarriena neighborhood s/n. 48940. Leioa. Bizkaia.