University of the Basque Country University of the Basque Country

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Equipment of the month: NovaSeq6000

The Illumina NovaSeq6000 (based on SBS-synthesis sequencing technology, responsible for up to 90% of the sequences currently deposited in scientific databases) is the most powerful, simple, scalable, and most powerful high-throughput sequencing platform. fast to date. It is, in turn, the platform that allows the longest reading length of all the maximum performance platforms currently available on the market.

The team located in the SGIker Genomics Service (UPV/EHU), completes the Massive sequencing platform available to date (MiSeq and NextSeq550, both from Illumina), covering the entire range of currently existing scales for conducting analyzes. NGS.

Its high productive performance together with its cost efficiency per data generated, will allow the research community to carry out projects and achieve objectives that were difficult to reach until now, and to apply this tool with great potential to the biosanitary field (diagnosis, treatment). Specifically, data-intensive applications, such as whole human genome sequencing (WGS), ultra-deep exome sequencing and normal and tumor profiling, de-novo large genome sequencing, ... could not be covered due to the equipment available up to now at the UPV/EHU, while with the incorporation of the NovaSeq6000, they can be carried out, since the equipment is adequate, not only technologically but also in a cost-efficient way, to obtain this type of results . Thus, the NovaSeq6000 has already been associated by many with the beginning of a new era of NGS.

The NovaSeq6000 will allow the achievement of large-scale NGS projects to the research community of the Basque Network of Science, Technology and Innovation. It will allow the opening of new lines of research, support existing ones and make it possible to tackle projects and objectives that have been economically and technologically unattainable until now. With this, a positive impact and growth of research projects, creation of new lines and groups, initiatives and expectations is expected.

Another great beneficiary will be the local health network. The incorporation of this infrastructure in the UPV/EHU will allow them to access, in a close and fast way, a technology of great potential, with especially promising applications in the area of ​​human health and public health

For more information, contact the UPV/EHU Genomics Service: