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ACS Applied Materials & Interfaces paper from Enrique! Congratulations!

First publication date: 20/02/2025

Congratulations Enrique! 

A new manuscript was recently published in ACS Applied Materials & Interfaces journal.

The paper entitled:  CellStudio: a Modular, Tunable and Accessible Platform for Analysis of Growth Factors Secretions in Cell Cultures by Enrique Azuaje-Hualde, Naiara Lartitegui-Meneses, Juncal Alonso-Cabrera, Asier Inchaurraga-Llamas, Yara Alvarez-Braña, Marian Martínez-dePancorbo,Fernando Benito-Lopez and Lourdes Basabe-Desmonts, presents CellStudio an innovative, user-friendly solution that exploits Printing and Vacuum Lithography combined with bead-based assays to create modular and tunable cell patterns surrounded by biosensors. This platform allows for high-resolution, spatially resolved analysis of secreted proteins, such as VEGF and FGF-2, while being easily implementable in standard laboratory settings. CellStudio’s design is compatible with conventional laboratory equipment, facilitating its integration into existing workflows without the need for extensive training or specialized tools. Validation experiments using mesenchymal stem cells and HeLa cells demonstrated that CellStudio can detect small secretion levels from small cell clusters with high sensitivity and analyze diffusion profiles, remarking the possibilities for studying cell behavior. By offering a standardized, cost-effective approach to detailed cellular analysis, CellStudio significantly enhances the capabilities of traditional cell culture techniques with broad applications across biological and biomedical research.