Specific skills:

1. Ability to improve in the knowledge of the structure, properties, preparation methods and main chemical reactions of organic compounds.

2. Ability to plan and carry out in the laboratory simple synthetic procedures and characterization of chemical compounds safely and using proper techniques, and to evaluate the data derived from experimental observations in the various fields of chemistry.

3. Ability to apply the basic principles of chemistry to industrial chemical operations and to chemical installation projects.



Transversal skills:

1. Ability to select and use several instrumental techniques for the characterization of chemical entities.

2. Ability to explain orally and in writing phenomena and processes related to Chemistry and associated subjects in an understandable way.

3. Ability to search for and select information in the field of Chemistry and other scientific fields using the literature sources and information technologies.

4. Ability to relate Chemistry to other disciplines, as well as to understand its positive impact on society and the importance of the chemical industrial sector.

Chapter 1. Introduction to Structure Determination by Spectroscopic methods



1.1. The electromagnetic spectrum

1.2. IR

1.3. UV-Vis

1.4. NMR

1.5. MS

1.6. Structure determination of organic compounds by spectroscopic techniques



Chapter 2. Chemistry of enols and enamines.



Chapter 3. Other C-C and C=C bond-forming reactions.



Chapter 4. Heterocyclic chemistry.



Chapter 5. Cycloadditions.



Laboratory sessions:



Session 1. Michael addition and aldol condensation. Structure determination (RMN, IR).

Session 2. Stereocontrolled reduction. Structure determination (RMN, IR).

Session 3. Acetonide. Structure determination (RMN, IR).

Session 4. Wittig reaction. Structure determination (RMN, IR).

Session 5. Synthesis of a heterocycle. Structure determination (RMN, IR).

In lectures, the student will be given the core concepts he/she needs to assimilate. The themes will be dealt with a selection of illustrative exercises that will be provided with sufficient advance notice for preparation as non-presence-based work.

The seminars are designed to make the best use of the laboratory sessions, in which the experimental work to be carried out will be examined in advance.

As described in Methods and Types of teaching, assessment of the subject in the ordinary call will be done based on the three sections, to which a percentage or specific weight will be assigned, and reflected in the final grade of the call. This assessment will be weighted as follows:



- Written test 60%

- Practical work (exercises, cases or problems) 30%

- Individual work 10% Two partial exams (January and May) (60%)

Laboratory (practical work + reports) and seminars (30%)

Classroom exercises (10%)



To pass the subject, you need to get a mark of at least 5.0 out of 10 in each section (independently). Passing partial exams, or even the final exam, does not guarantee that you will pass the subject, as the assessment also depends (for the remaining 40%) on the Laboratory, Seminars and Classroom work section.



The January and May exams will give an average grade, as will the five practical exercises and all classroom work that can be assessed. To reach the average mark of the two exams (January and May) you will need to score a minimum 5.0 in each one. Students who do not reach this grade will repeat the exam in the final ordinary call.



Furthermore, regarding the laboratory part, the student will be asked to make brief reports on the practical work in the laboratory. The practical work, the associated reports, the laboratory notebook and the exercises done in seminars and during the practical work will also be assessed.



As for classroom work, aspects to be considered are: attendance in class, participation in class, the gradual mastery of the competences to be acquired, and the performance by the student of illustrative exercises that will be collected and scored by the professor, as well as others done throughout the year.



The student will have the opportunity to withdraw from continuous (or combined) assessment and opt for a final assessment, regardless of whether he/she has participated (or not) in continuous assessment until then. To do this, the student must present his/her withdrawal to the professor responsible for the subject in a period that will end in week 18 of the academic year (as set in the Faculty of Science and Technology). This final assessment will consist of an overall exam covering all the aspects of the subjects, and will be taken within the official exam calendar.



Finally, students who decide to waive the opportunity to sit an an exam must indicate this in writing to the professor responsible for the subject before the end of week 18.

Lab coat, safety googles and lab notebook

Basic bibliography

1. J. I. Borrell, J. Teixidó, J. L. Falcó, SÍNTESIS ORGÁNICA, Síntesis, 2004.



2. M. Carda; S. Rodríguez; F. González; J. Murga; E. Falomir; E. CASTILLO, SÍNTESIS ORGÁNICA. RESOLUCIÓN DE

PROBLEMAS POR EL MÉTODO DE DESCONEXIÓN. Publicaciones de la Universitat Jaume I, Castellón, 1996



3. J. L. Marco, QUÍMICA DE LOS PRODUCTOS NATURALES, Síntesis 2006



4. T. L. Gilchrist QUÍMICA HETEROCÍCLICA. 2 ed. Addison-Wesley Iberoamericana, USA, 1995.



5. M. J. Rodríguez, F. Gómez, CURSO EXPERIMENTAL EN QUÍMICA ORGÁNICA, Síntesis, 2008.



6. M. A. Martínez, A. Csákÿ, TÉCNICAS EXPERIMENTALES EN SÍNTESIS ORGÁNICA, Síntesis, 2005.



7. SAFETY IN ACADEMIC CHEMISTRY LABORATORIES: VOLUME 1 y2. ACCIDENT PREVENTION FOR FACULTY

AND ADMINISTRATORS, 7ª Ed. American Chemical Society, Washington, DC, 2003



8. M. Hesse, H. Meier, B. Zeeh, MÉTODOS ESPECTROSCÓPICOS EN QUÍMICA ORGÁNICA, Síntesis, 2006.



9.2. P. Pretsch, C. Bühlmann, A. Affolter, R. Herrera, Martínez, Tablas para la determinación estructural por métodos espectroscópicos, Springer-Verlag Ibérica, 2001.

In-depth bibliography

1. S. Warren, P. Hyatt, ORGANIC SYNTHESIS: THE DISCONNECTION APPROACH, Wiley, 2008
2. F. A. Carey, R. J. Sundberg, ADVANCED ORGANIC CHEMISTRY, Partes A y B, 5ª Edición, Springer, 2007.
3. M. B. Smith, J. March, MARCH¿S ADVANCED ORGANIC CHEMISTRY: REACTIONS, MECHANISMS AND
STRUCTURE, 6ª Ed. Wiley, 2007.
4. R. Bruckner, ADVANCED ORGANIC CHEMISTRY: REACTION MECHANISMS, Academic Press, Londres, 2001.
5. J. A. Joule, K. Mills, HETEROCYCLIC CHEMISTRY, 4ª Ed., Blackwell Science, 2000
6. P. M. Dewick, MEDICINAL NATURAL PRODUCTS. A BIOSYNTHETIC APPROACH, 2ª Ed.,Wiley, Chichester, 2002.
7. R. M. Silverstein; F.X. Webster; D. Kiemle, SPECTROMETRIC IDENTIFICATION OF ORGANIC COMPUNDS, 7ª ed., Wiley & Sons, Nueva York, 2005
8. D. W. Williams; I. FLEMING, SPECTROSCOPIC METHODS IN ORGANIC CHEMISTRY, 6ª Ed., McGraw-Hill, Londres, 2007.

Journals

Organic Syntheses: http://www.orgsyn.org/
The Journal of Organic Chemistry: http://pubs.acs.org/journal/joceah
Organic Syntheses: http://www.orgsyn.org/
The Journal of Organic Chemistry: http://pubs.acs.org/journal/joceah
Organic Letters: http://pubs.acs.org/journal/orlef7
European Journal of Organic Chemistry: http://www3.interscience.wiley.com/journal/27380/home
Tetrahedron: http://www.sciencedirect.com/science/journal/00404020
Organic and Biomolecular Chemistry: http://www.rsc.org/Publishing/Journals/Ob/Index.asp
The Journal of Chemical Education: http://jchemed.chem.wisc.edu/
Organic Letters: http://pubs.acs.org/journal/orlef7
European Journal of Organic Chemistry: http://www3.interscience.wiley.com/journal/27380/home